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http://www.globalresearchonline.net/journalcontents/v23-2/60.pdf
Topical drug delivery systems include a large variety of pharmaceutical dosage form like semisolids, liquid preparation, sprays and solid powders. Most widely used semisolid preparation for topical drug delivery includes gels, creams and ointments. A gel is a cross-linked polymer network swollen in …
https://www.sciencedirect.com/science/article/pii/S0378517306002304
3. Gels as vaginal drug delivery systems. Vaginal drug delivery systems include a large variety of pharmaceutical forms such as semi-solids, tablets, capsules, pessaries, liquid preparations, vaginal films, vaginal rings, foams, and tampons. Most widely used semi-solid preparations for vaginal drug delivery include creams, ointments, and gels (Prista et al., 1996, Vermani and Garg, 2000).Author: J. das Neves, M.F. Bahia
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865781/
In situ forming polymeric formulations are drug delivery systems that are in sol form before administration in the body, but once administered, undergo gelation in situ, to form a gel. The formation of gels depends on factors like temperature modulation, pH change, presence of ions and ultra violet irradiation, from which the drug gets released in a sustained and controlled manner.
https://www.liebertpub.com/doi/10.1089/jwh.2004.13.834
Among the delivery systems proposed for this route is the use of intravaginal gels, which have been found to be potential vaginal drug delivery systems. The bioadhesives used in the formulation of gels play a key role in the release of the drug through the attachment to the vaginal mucosa, where the drug diffuses from the gel to the mucus.Author: Mary Justin-temu, Festo Damian, Renaat Kinget, Guy Van Den Mooter
https://pubag.nal.usda.gov/catalog/6826674
The successful construction of an anti-inflammatory pharmacologically active gel drug delivery system not only makes full use of the self-assembly properties and biological activity of natural products, but also provides an important reference for the development of pharmacologically active drug delivery systems using SSNPs in the future.
http://ijpsr.com/bft-article/formulation-and-development-of-liposomal-gel-for-topical-drug-delivery-system/?view=fulltext
Topical drug delivery system, designed to deliver a variety of drugs to the body through diffusion across the skin layers, is appealing for several reasons including avoidance of the variable absorption and metabolic breakdown associated with oral treatments, drug administration can be continuous, and minimal intestinal irritation can be avoided 8.
http://ijpsr.com/?action=download_pdf&postid=15321
drug delivery system. Although liposomes demonstrated promise for Topical drug delivery, the practical application of these formulations onto the skin is less. However, these can be incorporated into the gels than can be applied onto the skin. It has been found that liposomes incorporate into the gels …
https://www.slideshare.net/shreeraj9183/insitu-gel-drug-delivery-system
Aug 28, 2012 · Insitu gel Drug Delivery System By, Dr. Shreeraj Shah Associate Professor, Dept. of Pharmaceutical Technology, L. J. Institute of Pharmacy, Ahmedabad 1 2. Introduction It is a drug delivery system which is in a solution form before the administration in the body but it converts in to a gel form after the administration There are various routes ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618636/
Transdermal drug delivery system has recently been developed, aiming to achieve the objective of systemic medication through topical application to the intact skin surface. The skin acts as a major target as well as a principle barrier for transdermal drug delivery.
https://www.pharmatutor.org/articles/pharmaceutical-gels-in-summarized-form
Gels are used to achieve optimal cutaneous and percutaneous drug delivery. They can avoid gastrointestinal drug absorption difficulties caused by gastrointestinal pH. Gels are having property to avoid enzymatic activity and drug interaction with food and drinks.
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