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https://www.ncbi.nlm.nih.gov/pubmed/20437123
Ocular drug delivery. Gaudana R(1), Ananthula HK, Parenky A, Mitra AK. Author information: (1)Division of Pharmaceutical Sciences, School of Pharmacy, University of Missouri-Kansas City, 2464 Charlotte St., Kansas City, Missouri 64108-2718, USA.Author: Ripal Gaudana, Hari Krishna Ananthula, Ashwin Parenky, Ashim K. Mitra
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895432/
May 01, 2010 · Ocular drug delivery has been a major challenge to pharmacologists and drug delivery scientists due to its unique anatomy and physiology. Static barriers (different layers of cornea, sclera, and retina including blood aqueous and blood–retinal barriers), dynamic barriers (choroidal and conjunctival blood flow, lymphatic clearance, and tear dilution), and efflux pumps in conjunction pose a ...Author: Ripal Gaudana, Hari Krishna Ananthula, Ashwin Parenky, Ashim K. Mitra
https://link.springer.com/10.1208/s12248-010-9183-3
May 01, 2010 · Ocular drug delivery has been a major challenge to pharmacologists and drug delivery scientists due to its unique anatomy and physiology. Static barriers (different layers of cornea, sclera, and retina including blood aqueous and blood–retinal barriers), dynamic barriers (choroidal and conjunctival blood flow, lymphatic clearance, and tear dilution), and efflux pumps in conjunction pose a ...Author: Ripal Gaudana, Hari Krishna Ananthula, Ashwin Parenky, Ashim K. Mitra
https://www.researchgate.net/publication/44568159_Ocular_Drug_Delivery
Ocular drug delivery has been a major challenge to pharmacologists and drug delivery scientists due to its unique anatomy and physiology. Static barriers (different layers of cornea, sclera, and ...
https://www.sciencedirect.com/science/article/pii/B9780128162002000050
Systemic ocular drug delivery: Systemic drug delivery is another option for the treatment of ocular disorders and is mostly preferred for the treatment of posterior segment diseases. However, it has disadvantages such as serious systemic side effects, blood–ocular barriers limit the efficacy of the drug particularly to the posterior segments.Author: Yıldız Özsoy, Sevgi Güngör, Emine Kahraman, M. Ezgi Durgun
https://link.springer.com/article/10.1007%2Fs11095-008-9694-0
Aug 29, 2008 · Ocular drug delivery has remained as one of the most challenging task for pharmaceutical scientists. The unique structure of the eye restricts the entry of drug molecules at the required site of action. Drug delivery to the eye can be broadly classified into anterior and posterior segments (Fig. 1).Author: Ripal Gaudana, J. Jwala, Sai H. S. Boddu, Ashim K. Mitra
https://www.sciencedirect.com/science/article/pii/S2211383516300855
3. Benefits and limitations of ocular delivery routes 3.1. Systemic administrations. Intravenous injection and oral dosing are known systemic administration methods for ocular drug delivery. Since the choroid of the eye has a vascular choroid plexus structure, drugs can easily enter the choroid through blood vessels.Author: Yuhua Weng, Juan Liu, Shubin Jin, Weisheng Guo, Xingjie Liang, Zhongbo Hu
https://drug-dev.com/eyesol-a-novel-topical-ocular-drug-delivery-system-for-poorly-soluble-drugs/
Therefore, a non-protic, aqueous-free ocular delivery system has the potential to provide an alternative approach in particular for poorly soluble drugs. EYESOL(TM) OCULAR DRUG DELIVERY PLATFORM. EyeSolTM, Novaliq’s proprietary ocular drug delivery technology, offers such an alternative.
https://pharmachitchat.wordpress.com/2015/05/27/drug-design-concept-ocular-drug-delivery/
May 27, 2015 · Drug Design Concept – Ocular Drug Delivery. Posted on May 27, 2015 Updated on May 27, 2015. About Authors: * 1 Ronak Patel, 2 Mr. Ripal Mistry 1 M.Pharm, Bhupal Nobels’ College Of Pharmacy, Udaipur 313001 2 M.pharm, Indubhai Patel College Of Phaarmacy And Research Center, Dharmaj *[email protected]. Abstract: Ocular administration of the drug is primarily associated with …
http://www.nanovexbiotech.com/plga-nanoparticles-ocular-drug-delivery/
Nov 14, 2017 · PLGA nanoparticles in the ocular drug delivery The topical ocular administration of drugs has two different purposes: to treat superficial eye diseases, such as infections (e.g. conjunctivitis, blepharitis, keratitis sicca) and to provide intraocular treatment through the cornea for diseases such as glaucoma or uveitis.Compared with drug delivery to other parts of the body, ocular …
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