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https://www.researchgate.net/publication/8573923_Gastroretentive_Delivery_Systems_Hollow_Beads
Most of the floating systems previously reported are single unit systems such as tablets and capsules. A drawback of these systems is the high variability of the GI transit time due to their all ...
https://www.slideshare.net/akashaher07/1-gastroretentive-drug-delivery-systems
Jun 08, 2013 · 1 gastroretentive drug delivery systems ... Volatile liquid containing systems Gas generating systems Non-Effervescent Colloidal gel barrier systems Alginate beads Hollow Microspheres Microporous Compartment System ... drug delivery via gastric retention. J.Controlled Release. 2000, 63, 235-25• Nayak Amit, Maji Ruma and Das Biswarup ...
https://www.researchgate.net/publication/202883617_Gastroretentive_drug_delivery_systems_A_review
The purpose of writing this review on gastroretentive drug delivery systems was to compile the recent literature with special focus on various gastroretentive approaches that have recently become ...
https://www.tandfonline.com/doi/abs/10.3109/03639045.2013.763817
Apr 28, 2015 · (2014). Development of novel gastroretentive drug delivery system of gliclazide: hollow beads. Drug Development and Industrial Pharmacy: Vol. 40, No. 3, pp. 398-408.Author: Rajendra Awasthi, Giriraj T. Kulkarni
http://www.authorstream.com/Presentation/Parthjoshi-898323-gastroretentive-drug-delivery-system/
Mar 19, 2011 · A. Floating Drug Delivery System : Floating drug delivery systems (FDDS) have a bulk density less than gastric fluids and so remain buoyant in the stomach without affecting the gastric emptying rate for a prolonged period of time.
https://innovareacademics.in/journal/ajpcr/Vol3Issue1/250.pdf
we have reviewed various gastroretentive approaches designed and developed until now, i.e. high density (sinking), floating, bio- or mucoadhesive, expandable, unfoldable, super porous hydrogel and magnetic systems. Finally, advantages of gastroretentive drug delivery systems were covered in detail.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3845978/
Hollow microspheres for gastroretentive floating- pulsatile drug delivery: preparation and in vitro evaluation ... Oral pulsatile drug delivery systems that release drug after a lag period of 6–7 h usually release drug in large ... . 18 Buoyancy of beads is directly related to performance of floating-pulsatile drug delivery system since lag ...Author: Maryam Maghsoodi, Elham Hemati, Bahram Qadermazi, Zahra Yari
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523542/
Apr 20, 2019 · In recent years, many attempts have been made to enhance the drug bioavailability and therapeutic effectiveness of oral dosage forms. In this context, various gastroretentive drug delivery systems (GRDDS) have been used to improve the therapeutic efficacy of drugs that have a narrow absorption window, are unstable at alkaline pH, are soluble in acidic conditions, and are active locally …Author: Julu Tripathi, Prakash Thapa, Ravi Maharjan, Seong Hoon Jeong
https://www.sciencedirect.com/science/article/pii/S1818087616300320
Gastro-retentive drug delivery system (GRDDS) has gained immense popularity in the field of oral drug delivery recently. It is a widely employed approach to retain the dosage form in the stomach for an extended period of time and release the drug slowly that can address many challenges associated with conventional oral delivery, including poor bioavailability.Author: Uttam Kumar Mandal, Bappaditya Chatterjee, Faria Gias Senjoti
http://ijpsr.com/bft-article/gastroretentive-drug-delivery-system-an-approach-to-enhance-gastric-retention-for-prolonged-drug-release/?view=fulltext
Gastroretentive drug delivery system is novel drug delivery systems which has an upper hand owing to its ability of prolonged retaining ability in the stomach and thereby increase gastric residence time of drugs and also improves bioavailability of drugs.
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