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https://innovareacademics.in/journal/ajpcr/Vol3Issue1/250.pdf
Floating drug delivery systems Floating drug delivery systems is one of the important approaches to achieve gastric retention to obtain sufficient drug bioavailability [25]. This delivery systems is desirable for drugs with an absorption window in the stomach or in the upper small intestine [26].
http://pharmaquest.weebly.com/uploads/9/9/4/2/9942916/grdds.pdf
Gastro-retentive delivery is one of the site specific delivery for the delivery of drugs either at stomach or at intestine. It is obtained by retaining dosage form into stomach and drug is being released at controlled manner to specific site either in stomach, duodenum and intestine.
http://www.authorstream.com/Presentation/v.ramani007-1665945-gastro-retentive-drug-delivery-system/
Feb 05, 2013 · Floating Drug Delivery System FOOD INTAKE AND NATURE OF THE FOOD Usually the presence of food increases the GRT (Gastric retention time) of the dosage form and increases drug absorption by allowing it to stay at the absorption site for a longer time. Floating Drug Delivery System EFFECT OF GENDER,...
https://www.ijrpsonline.com/pdf/7007.pdf
Advantages of Gastro/Intestinal retentive Delivery Systems Improvement of bioavailability and therapeutic efficacy of the drugs and possible reduction of dose. Maintenance of constant therapeutic levels over a prolonged period and thus reduction in fluctuation in therapeutic levels.
http://www.authorstream.com/Presentation/Parthjoshi-898323-gastroretentive-drug-delivery-system/
Mar 19, 2011 · The major requirements for floating drug delivery system 15 GRDDS A. Floating Drug Delivery System : Floating drug delivery systems (FDDS) have a bulk density less than gastric fluids and so remain buoyant in the stomach without affecting …
https://www.pharmatutor.org/pdf_download/pdf/Vol.%204,%20Issue%207,%20July%202016,%20PharmaTutor,%20Paper-3.pdf
conventional oral delivery systems have some limits related to fast gastric emptying time. Gastroretentive dosage form is a type of novel drug delivery system which can persist in the stomach for prolonged period of time and thus increases the GRT of drugs. Gastro-retention helps to improve bioavailability of drugs.
https://www.slideshare.net/GajananSanap/gastro-retentive-drug-delivery-system
Feb 27, 2016 · Gastro-retentive delivery is one of the site specific delivery of the drugs at stomach. It is obtained by retaining dosage form into stomach and drug is being released at sustained manner to specific site either in stomach or intestine.
https://www.researchgate.net/publication/229033572_Gastroretentive_Drug_Delivery_System_An_Overview
Gastro retentive drug delivery systems have potential to permit improved penetration of the mucus layer and as a result better concentration of drug at the specific site ,ensure optimal ...
https://www.slideshare.net/akashaher07/1-gastroretentive-drug-delivery-systems
Jun 08, 2013 · 32. ConclusionGastro retentive drug delivery systems are the mostpreferable systems in order to deliver the drugs whichhave a narrow absorption window near the gastricregion. Now a days a number of drug delivery devicesare being developed which aim at releasing the drug …
http://www.thepharmajournal.com/vol1Issue8/Issue_oct_2012/4.1.pdf
reducing the dosing frequency and minimizing fluctuation in plasma drug concentration at steady state by delivering the drug in a controlled and reproducible manner.2 One novel approach in this area is GRDDSs (gastro retentive drug delivery system). Dosage forms that can be retained in the stomach are called GRDDs.
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