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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2750381/
Oct 19, 2005 · The purpose of writing this review on floating drug delivery systems (FDDS) was to compile the recent literature with special focus on the principal mechanism of floatation to achieve gastric retention. The recent developments of FDDS including the physiological ...Author: Shweta Arora, Javed Ali, Alka Ahuja, Roop K. Khar, Sanjula Baboota
https://www.pharmamirror.com/pharmacy/pharmaceutics-floating-drug-delivery-systems/
Floating drug delivery systems (FDDS) have a bulk density less than gastric fluids and so remain buoyant in the stomach without affecting gastric emptying rate for a prolonged period of time. While the system is floating on the gastric contents, the drug is released slowly at the desired rate from the system.
https://www.researchgate.net/publication/285161997_Gastric_floating_drug_delivery_systems_A_review
Gastric floating drug delivery systems: A review ... Many approaches are utilized in the development of gastric retention drug delivery systems viz. hydrodynamically balanced systems, swelling ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178975/
A multiple unit oral floating drug delivery system of famotidine was developed to prolong gastric residence time, target stomach mucosa and increase drug bioavailability. Drug and polymer compatibility was studied by subjecting physical mixtures of drug and polymers to differential scanning calorimetry.
https://pharmacophorejournal.com/storage/models/article/cG1bD2zldr2XKpMeNXltjKsDy3MIomlPHtTuUKuJssCcBoa5MTA0yalzq12Z/floating-drug-delivery-system-a-review.pdf
50% of the drug delivery systems available in the market are oral drug delivery systems.1 Floating systems or hydrodynamically controlled systems are low-density systems that have sufficient buoyancy to float over the gastric contents and remain buoyant in the stomach without affecting the gastric emptying rate for a prolonged periodFile Size: 1MB
https://www.sciencedirect.com/science/article/pii/S0144861719303509
Desired floating in gastric fluids is the key to a successful gastric-floating drug delivery system. For ideal gastric floating, the system should float for 5 min and can then maintain the floating state for 8 h in a simulated gastric fluid (SGF).Author: Jinchuan Xu, Xiaoyan Tan, Ling Chen, Xiaoxi Li, Fengwei Xie, Fengwei Xie
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