Formulation Of Ocular Drug Delivery System

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Ocular drug delivery systems: An overview

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289909/
    The major challenge faced by today’s pharmacologist and formulation scientist is ocular drug delivery. Topical eye drop is the most convenient and patient compliant route of drug administration, especially for the treatment of anterior segment diseases.Author: Ashaben Patel, Kishore Cholkar, Vibhuti Agrahari, Ashim K Mitra

Drug Delivery System - an overview ScienceDirect Topics

    https://www.sciencedirect.com/topics/nursing-and-health-professions/drug-delivery-system
    Drug Delivery System. A drug delivery system (DDS) is defined as a formulation or a device that enables the introduction of a therapeutic substance into the body and improves its efficacy and safety by controlling the rate, time, and place of release of drugs in the body.

Advanced Formulation Approaches for Ocular Drug Delivery ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781321/
    Sep 06, 2019 · For quite a few decades, the mechanism of specific drug delivery to ocular milieu was indeed a challenge [201,202]. The common pharmaceutical formulations applied to this purpose, drugs applied as eye drops, suffered downsides which, by turn, required the implementation of distinct carriers aimed in ocular administration route.Author: Eliana B. Souto, João Dias-Ferreira, Ana López-Machado, Miren Ettcheto, Amanda Cano, Antonio Camins ...

ocular drug delivery systems - SlideShare

    https://www.slideshare.net/vijayalakshmikalaga/ocular-drug-delivery-systems
    Sep 17, 2012 · ocular drug delivery systems 1. INTRODUCTION Ocular administration of drug isprimarily associated with the need totreat ophthalmic diseases. Eye is the most easily accessible site fortopical administration of a medication. Ideal ophthalmic drug delivery mustbe able to sustain the drug release andto remain in the vicinity of front of theeye for prolong period of time.

(PDF) OCULAR DRUG DELIVERY SYSTEM – A REVIEW

    https://www.researchgate.net/publication/225897418_OCULAR_DRUG_DELIVERY_SYSTEM_-_A_REVIEW
    A successful design of a drug delivery system, therefore, requires an integrated knowledge of the drug molecule and the constraints offered by the ocular route of administration [3].

Safety Evaluation of Ocular Drug Delivery Formulations ...

    https://journals.sagepub.com/doi/pdf/10.1177/0192623307310955
    Vol. 36, No. 1, 2008 OCULAR DRUG DELIVERY FORMULATIONS 51 FIGURE 3.—Sites and methods for ocular drug delivery to the eye. Various methods for delivery of drugs to the anterior and posterior chambers of the eye are illustrated, including sites for conventional drug delivery as well as newer routes. Reproduced by permission from Davis et al ...

DRUG DELIVERY - EyeSol: a Novel Topical Ocular Drug ...

    https://drug-dev.com/eyesol-a-novel-topical-ocular-drug-delivery-system-for-poorly-soluble-drugs/
    All-in-all, this leaves a very limited formulation window for aqueous-based ocular drug delivery, including emulsions and suspensions. Therefore, a non-protic, aqueous-free ocular delivery system has the potential to provide an alternative approach in particular for poorly soluble drugs. EYESOL(TM) OCULAR DRUG DELIVERY PLATFORM

Design principles of ocular drug delivery systems ...

    https://www.sciencedirect.com/science/article/pii/S1359644618303994
    Ocular drug delivery is a field in which regular ADME tools are not useful. • Pharmacokinetics based dosing aid for ocular drug delivery is presented. • User-friendly dosing aid guides early stage design of delivery systems. • Guidance for the delivery route, dosing and formulation design is presented.Author: Astrid Subrizi, Astrid Subrizi, Eva M. del Amo, Viktor Korzhikov-Vlakh, Tatiana Tennikova, Marika Ru...

Ocular drug delivery system ppt - SlideShare

    https://www.slideshare.net/RikeshlalShrestha/ocular-drug-delivery-system-ppt
    Apr 04, 2017 · FORMULATION APPROACHES TO IMPROVE OCULAR BIOAVAILABILITY Approaches to improve the ocular bioavailability have been attempted in two directions: To increase the corneal permeability To prolong the contact time with the ocular surface Conventional Dosage Forms Polymeric Delivery System Solutions Viscosity - Enhancing Polymers Suspensions ...

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