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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3053525/
The mucoadhesive dosage forms offer prolonged contact at the site of administration, low enzymatic activity, and patient compliance. The formulation of mucoadhesive drug delivery system depends on the selection of suitable polymer with excellent mucosal adhesive properties and biocompatibility.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255397/
Mucoadhesive drug delivery systems interact with the mucus layer covering the mucosal epithelial surface, and mucin molecules and increase the residence time of the dosage form at the site of absorption. The drugs which have local action or those which have maximum absorption in gastrointestinal tract (GIT) require increased duration of stay in GIT.
https://www.jgtps.com/admin/uploads/J4ZRkQ.pdf
mucoadhesive drug delivery system for the delivery of Nateglinide in a non-invasive dosage form with enhanced bioavailability that bypasses the hepatic first pass metabolism by delivering the drug unidirectionally towards buccal mucosa. Drug-polymer interaction studies through substantial observation, FTIR analysis revealed that
https://www.scribd.com/presentation/27509697/Formulation-and-Evaluation-of-Mucoadhesive-Drug-Delivery-Systems
Formulation and Evaluation of. MUCOADHESIVE DRUG DELIVERY SYSTEMS Introduction Novel drug delivery systems (NDDS) are the system where the man searches for new methods of entry of drugs in to the body in order to show its activity in the body . The new drug delivery systems that have been developed...3.5/5(3)
http://www.scielo.br/pdf/bjps/v46n1/02.pdf
Mucoadhesive drug delivery systems 3 the contact between the mucoadhesive and the mucous membrane, with spreading and swelling of the formu-lation, initiating its deep contact with the mucus layer (Hägerstrom, 2003). In some cases, such as for ocular or vaginal formulations, the delivery system is mechanically attached over the membrane.
https://www.sciencedirect.com/science/article/pii/S0141813020306723
Hyaluronic Acid Based Mucoadhesive Self Nanoemulsifying Drug Delivery System (SNEDDS) of Tamoxifen showed prolong release of TMX over an extended time period. Based on the findings, designed TMX-PAP-HA-ss-LCA SNEDDS formulation seems to be valuable system regarding mucopermeation, augmented cellular uptake, non-toxic nature and enhanced anti-cancer activity.Author: Ayesha Batool, Rabia Arshad, Sobia Razzaq, Kainat Nousheen, Maria Hassan Kiani, Gul Shahnaz
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