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http://www.pharmtech.com/formulation-lactose-inhaled-delivery-systems
Nov 01, 2002 · These three requirements dictate the formulation of the powder to be inhaled, of which lactose is a major constituent. Therefore, lactose for inhalation has to meet some basic requirements, which are discussed in this article. Inhalation using a DPI From a …
https://www.researchgate.net/publication/286156771_Formulation_of_lactose_for_inhaled_delivery_systems
The quality of lactose, that is to say sieved or milled quality, used for the formulation of an inhalation powder may affect the aerodynamic behaviour of drug/lactose blends (Steckel et al., 2004 ).
https://www.ncbi.nlm.nih.gov/pubmed/11745794
Lactose as a carrier in dry powder formulations: the influence of surface characteristics on drug delivery. Zeng XM(1), Martin GP, Marriott C, Pritchard J. Author information: (1)Department of Pharmacy, King's College London, Franklin-Wilkins Building, 150 Stamford Street, London, SE1 9NN, United Kingdom.Author: Xian Ming Zeng, Gary P. Martin, Christopher Marriott, John Pritchard
https://www.sciencedirect.com/science/article/pii/S0378517310001912
Formulation strategy and use of excipients in pulmonary drug delivery. Author links open overlay panel Gabrielle Pilcer Karim Amighi. Show more. ... DPIs are a widely accepted inhaled delivery dosage form, ... A. ChambersComparison of lactose free formulation of sodium cromoglycate and sodium cromoglycate plus lactose in the treatment of asthma.Author: Gabrielle Pilcer, Karim Amighi
https://www.sciencedirect.com/science/article/pii/S0169409X14002300
Inhaled formulations and pulmonary drug delivery systems for respiratory infections ... The lactose in Relenza® formulation triggered ventilator occlusion causing the patient to have severe hypoxemia ... DPIs are also becoming popular and have attracted rising interest in recent years for the delivery of inhaled high-dose antibiotics. Their ...Author: Qi (Tony) Zhou, Sharon Shui Yee Leung, Patricia Tang, Thaigarajan Parumasivam, Zhi Hui Loh, Hak-Kim ...
https://www.researchgate.net/publication/269177119_Inhaled_formulations_and_pulmonary_drug_delivery_systems_for_respiratory_infections
In recent years, inhaled drug delivery has attracted increasing interest by the pharmaceutical industry and at present, several inhalable drug delivery systems (liposomes) are in advanced stages ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1884297/
Apr 18, 2002 · Pulmonary delivery devices. The lung has served as a route of drug administration for thousands of years. The origin of inhaled therapies can be traced back 4000 years ago to India, where people smoked the leaves of the Atropa belladonna plant to suppress cough. In the 19th and early 20th centuries, asthmatics smoked asthma cigarettes that contained stramonium powder mixed with …Author: N. R. Labiris, M. B. Dolovich
http://www.pharmtech.com/developing-orally-inhaled-dry-powder-formulation-complex-itinerary-and-technological-challenge
Jun 02, 2015 · mona plougmann/E+/Getty Images The delivery of an orally inhaled API to the deep lung can be performed using different drug-delivery platforms, such as nebulizers, pressurized metered dose inhalers (pMDI), and dry powder inhalers (DPI). DPIs are increasingly becoming a more important drug delivery option and are expected to hit double-digit figures, reaching global sales of $31.5 billion in ...
https://www.ondrugdelivery.com/selection-excipients-dry-powder-inhalers/
Citation: Peters H, Hebbink G, “Selection of Excipients For Dry Powder Inhalers”. ONdrugDelivery Magazine, Issue 72 (Dec 2016), pp 34-36. Harry Peters and Gerald Hebbink explain how, because dry powder inhalers need a carrier to help with ensuring the drug is effectively delivered, interest has been focused on developing inhalation-grade lactose for this purpose, and examine which ...
https://www.pharmaexcipients.com/excipient-for-inhalation/
Building on a long and well established history of supplying world class pharmaceutical grade lactose, film coatings, and tableting systems, Kerry introduces Aero Flo® Inhalation lactose, designed to meet the growing demand for lactose that is suitable for developing dry powder inhalers. ... (DPI) formulation for pulmonary delivery. Lactose ...
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