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https://www.researchgate.net/publication/10885206_Follicular_liposomal_delivery_sytems
Request PDF Follicular liposomal delivery sytems Traditionally, the prime pathway for the topical delivery of active agents across the skin was thought to be through intercellular routes and ...
https://www.sciencedirect.com/science/article/pii/S0022202X15329997
Liposomes had been widely used for drug delivery in the past. In this study, five different liposomes were used as a follicular delivery system in pig ear skin. The liposomes mainly differed in their sphere diameter, lipid composition, and surface charge.Author: Sascha Jung, Nina Otberg, Gisela Thiede, Heike Richter, Wolfram Sterry, Steffen Panzner, Jürgen Lade...
https://www.jidonline.org/article/S0022-202X(15)32999-7/pdf
Liposomes had been widely used for drug delivery in the past. In this study, five different liposomes were used as a follicular delivery system in pig ear skin. The liposomes mainly differed in their sphere diameter, lipid composition, and surface charge.
https://www.dovepress.com/transfollicular-drug-delivery-current-perspectives-peer-reviewed-fulltext-article-RRTD
The follicular region is the most approachable site for drug delivery via liposomes. 82,83 Over a decade ago, Balsari et al reported that liposomes modified with monoclonal antibodies were used as a protective measure for alopecia induced by doxorubicin in rats. 84 Li and Hoffman found that calcein-, melanin-, and DNA-loaded liposomes improved the accumulation of each penetrant inside the …
https://www.tandfonline.com/doi/abs/10.3109/03639045.2015.1082580
AbstractBackground: Adapalene is a widely used topical anti-acne drug; however, it has many side effects. Liposomal drug delivery can play a major role by targeting delivery to pilosebaceous units,...Author: Vijay Kumar, Ajay K. Banga
https://www.naturalmedicinejournal.com/blog/secret-effective-liposomal-delivery
In one study, cellular intake increased 9-fold as the liposome size was decreased from 236 nm to 97 nm, and cellular intake was increased 34-fold at 64 nm. 3 In addition, the therapeutic capabilities of a liposomal delivery system are also related to how fast the body clears the liposomes from the blood.
https://www.tandfonline.com/doi/abs/10.3109/10611869408996816
Mar 21, 2012 · This review will highlight work done in our laboratories evaluating topical liposomal delivery in a wide variety of animal models and human skin using both in vivo and in vitro techniques. The mechanism by which liposomes facilitate deposition of drugs into the skin and some potential applications of topically applied liposomes will be discussed.Author: N. Weiner, L. Lieb, S. Niemiec, C. Ramachandran, Z. Hu, K. Egbaria
https://www.sciencedirect.com/science/article/pii/S037851730600425X
Better understanding of the control mechanisms, which govern the complex structure of the pilosebaceous unit, will help designing more rationally the hair follicle-specific drug delivery systems. However, in order to truly ascertain the significance of follicular delivery, appropriate models and quantitative methods must still be developed.Author: Majid Tabbakhian, Naser Tavakoli, Mahmoud Reza Jaafari, Saeid Daneshamouz
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934386/
Feb 09, 2014 · Microsponge delivery system when applied to the skin, the release of drug can be controlled through diffusion or other variety of triggers, including rubbing, moisture, pH, friction, or ambient skin temperature . Controlled release of drug from a delivery system to the skin could reduce the side effect while reducing percutaneous absorption.Author: Amber Vyas, Avinesh Kumar Sonker, Bina Gidwani
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