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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539067/
Oct 18, 2012 · Nasal delivery is the logical choice for topical treatment of local diseases in the nose and paranasal sinuses such as allergic and non-allergic rhinitis and sinusitis. The nose is also considered an attractive route for needle-free vaccination and for systemic drug delivery, especially when rapid absorption and effect are desired.Author: Per Gisle Djupesland
https://www.sciencedirect.com/topics/medicine-and-dentistry/nasal-vaccine
For example, nasal delivery permits acquisition of significant serum levels of IL-12 at one-tenth the dose required for inhibition of serum IFN-γ by parenteral administration. 1 A nasal vaccine of tetanus toxoid (TT), given with either IL-6 or IL-12, induced serum TT-specific IgG Ab responses that protected mice against lethal challenge with ...
https://www.ondrugdelivery.com/wp-content/uploads/2018/11/Nov2005.pdf
NASAL DELIVERY TECHNOLOGY: ANATOMY + INNOVATIVE DEVICE = ADDED VALUE OPPORTUNITY Direct-Haler A/S has invented and developed a novel nasal delivery device and nasal delivery principle. The innovation takes advantage of the patient’s anatomy to improve nasal delivery effectiveness and convenience.
https://www.amazon.com/First-Defense-Nasal-Screens-Pick/dp/B00JZVC5EO
Apr 18, 2017 · The air doesn't smell like allergy anymore and my nasal didn't act up at all during the game. It's when I got back home and took off the screen my nasal started acting up slowly, this time I guess due to the pollen left on my clothes. Thank you First Defense for saving my hobby and I will make sure I put one on every time before a game.3.6/5(29)
https://www.optinose.com/exhalation-delivery-systems/nasal-delivery-challenges
Nasal Delivery Challenges Despite easy access, the complex and dynamic geometry of the nose makes reliable and efficient delivery of drugs to mucosal surfaces high and deep in the nose challenging. The nasal valve is the narrowest segment of the respiratory tract, accounting for up to 80% of nasal resistance and almost half of total respiratory ...
https://www.amazon.com/First-Defense-Nasal-Screens-7-Sets/dp/B004KQF9QA
Nov 26, 2018 · Buy First Defense Nasal Screens, 7-Sets Per Pack on Amazon.com FREE SHIPPING on qualified orders3.6/5(440)
http://intranasal.net/Overview/default.htm
Yuen et al report that in 5.3% of pediatric patients they were unable to dispense drops into the nose due to resistance to this delivery technique.[13] While nasal delivery is possible the majority of the time, to overcome these delivery issues a number of device have been developed that enhance delivery - these are discussed in the delivery ...
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