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https://www.sciencedirect.com/science/article/pii/S0378517313004602
Film coatings for oral colon delivery. ... Oral colon delivery is pursued through a number of formulation strategies with the aim of enabling effective and well-tolerated treatments for large bowel pathologies or enhancing the intestinal absorption of peptide and protein drugs. According to such strategies, coated dosage forms for colonic ...Author: Alessandra Maroni, Maria Dorly Del Curto, Lucia Zema, Anastasia Foppoli, Andrea Gazzaniga
https://www.researchgate.net/publication/237003330_Film_Coatings_for_Oral_Colon_Delivery
Film Coatings for Oral Colon Delivery. ... The first proof of concept in vivo for a new type of microbiota-sensitive film coatings allowing for colon targeting is presented. The efficacy of these ...
https://www.sciencedirect.com/science/article/pii/S1773224714000069
Because of their spherical or pseudo-spherical shape, uniform size and smooth surface, pellets are of particular interest for use as cores in the manufacturing of coated oral delivery systems. When intended for colon delivery, pellet formulations may be provided with enzymatically-degradable, pH-sensitive or time-controlled polymer coatings.Author: Luca Palugan, Matteo Cerea, Lucia Zema, Andrea Gazzaniga, Alessandra Maroni
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2750350/
Amylose-ethylcellulose film coatings obtained from organic-based solvents were investigated as potential vehicles for colonic drug delivery. Amylose, in the form of an amylose-butan-1-ol dispersion, and ethylcellulose, dissolved in either ethyl lactate, ethanol, or propanol and plasticized with dibutyl sebacate, were mixed in various proportions and applied using a fluidized bed coater to ...Author: Lee F. Siew, Abdul W. Basit, J. Michael Newton
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508299/
Jun 13, 2015 · Colon-specific drug delivery systems (CDDS) are desirable for the treatment of a range of local diseases such as ulcerative colitis, Crohn’s disease, irritable bowel syndrome, chronic pancreatitis, and colonic cancer. In addition, the colon can be a potential site for the systemic absorption of several drugs to treat non-colonic conditions.Author: Seth Amidon, Jack E. Brown, Vivek S. Dave
https://www.deepdyve.com/lp/elsevier/film-coatings-for-oral-colon-delivery-bolk2rAOc7
Dec 05, 2013 · Read "Film coatings for oral colon delivery, International Journal of Pharmaceutics" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.
https://www.researchgate.net/publication/225408781_The_potential_of_organic-based_amylose-ethylcellulose_film_coatings_as_oral_colon-specific_drug_delivery_systems
The potential of organic-based amylose-ethylcellulose film coatings as oral colon-specific drug delivery systems Article (PDF Available) in AAPS PharmSciTech 1(3):53-61 · September 2000 with 65 Reads
https://www.deepdyve.com/lp/elsevier/film-coatings-for-oral-pulsatile-release-iYcfU5uezR
Dec 05, 2013 · Read "Film coatings for oral pulsatile release, International Journal of Pharmaceutics" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.
https://pubs.acs.org/doi/10.1021/jf2005468
An oral colon-targeting controlled release system based on resistant starch acetate (RSA) as a film-coating material was developed. The RSA was successfully synthesized, and its digestion resistibility could be improved by increasing the degree of substitution (DS), which was favorable for the colon-targeting purpose. As a delivery carrier material, the characteristics of RSA were investigated ...Author: Huayin Pu, Ling Chen, Xiaoxi Li, Fengwei Xie, Long Yu, Lin Li
http://discovery.ucl.ac.uk/1367955/
Basit, AW; (2000) Oral colon-specific drug delivery using amylose-based film coatings. Pharmaceutical Technology Europe, 12 (2) . Full text not available from this repository. Abstract. In recent years, oral drug delivery to the colon has become an increasingly important avenue of investigation.
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