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https://www.sciencedirect.com/journal/advanced-drug-delivery-reviews/vol/29/issue/1
Read the latest articles of Advanced Drug Delivery Reviews at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature
https://www.pharmatutor.org/articles/nasal-drug-delivery-system-complete-review
Hydrophobic and low molecular drugs can easily penetrate through nasal mucosa with less degradation. Fast absorption can be achieved due to large absorption surface area and high vascularisation. In emergency nasal route can be used as alternative route of …
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http://japer.sperpublications.com/oldjaper/Issue/issues%204oct-des%202013/148.pdf
Limitations of nasal drug delivery system • Delivery volume in nasal cavity is restricted to 25–200 μL. • High molecular weight compounds cannot be delivered through this route (mass cut off ~1 kDa). • Adversely affected by pathological conditions. • Large interspecies variability is observed in this route.File Size: 845KB
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539067/
Oct 18, 2012 · Nasal delivery is the logical choice for topical treatment of local diseases in the nose and paranasal sinuses such as allergic and non-allergic rhinitis and sinusitis. The nose is also considered an attractive route for needle-free vaccination and for systemic drug delivery, especially when rapid absorption and effect are desired.Author: Per Gisle Djupesland
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161189/
Aug 03, 2018 · Tailoring Formulations for Intranasal Nose-to-Brain Delivery: A Review on Architecture, Physico-Chemical Characteristics and Mucociliary Clearance of the Nasal Olfactory Mucosa ... route ② is rather slow. Thus, it is most likely not the primary route of delivery, as it has been shown that the N2B delivery is quite fast ... Devices as the ...Author: Stella Gänger, Katharina Schindowski
https://www.researchgate.net/publication/49601002_Nasal_drug_delivery_system_-_an_overview
The use of the nasal route for the delivery of challenging drugs such as small polar molecules, vaccines, hormones, peptides and proteins has created much interest in nowadays. Due to the high permeability, high vasculature, low enzymatic environment of nasal cavity and avoidance of hepatic first pass...
https://www.researchgate.net/publication/281614394_Nanoparticles_Nasal_Delivery_of_Drugs
Nanoparticles: Nasal Delivery of Drugs. Diseases of the Central Nervous System (CNS) such as schizophrenia, meningitis, migraine, parkinson's disease and alzheimer's disease require delivery of the drug to the brain for treatment. Treatment of CNS diseases are difficult because of presence of blood – brain barrier (BBB).
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