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https://www.sciencedirect.com/science/article/pii/S0168365997001533
Eutectic mixtures of ibuprofen and enhancer were selected to investigate the effects of melting point depression of the two-component delivery system on transdermal drug delivery. Percutaneous delivery of ibuprofen is well characterised 9, 10and it is the active ingredient in a …Author: Paul W Stott, Adrian C Williams, Brian W Barry
https://www.ncbi.nlm.nih.gov/pubmed/9685897
Jan 02, 1998 · The formation of eutectic systems between ibuprofen (ibu) and seven terpene skin penetration enhancers was studied and, by using the eutectic systems as donors, the effects of melting point depression of the delivery system on transdermal delivery were investigated.Author: Paul W Stott, Adrian C Williams, Brian W Barry
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976748/
May 06, 2013 · Transdermal drug delivery is one of these patient-friendly methods of drug delivery which provides several advantages over oral and injectable routes . These advantages include decreasing the food-drug intera-ction, premature metabolism in the gut wall and liver, avoiding needles and subsequent complications as well as the large surface area available for systemic and controlled drug delivery …Author: Soliman Mohammadi-Samani, Gholamhossein Yousefi, Farhad Mohammadi, Fatemeh Ahmadi
https://scinapse.io/papers/1996891718
Jan 02, 1998 · Abstract The applications of eutectic systems, including deep eutectic solvents (DESs), in diverse sectors have drawn significant interest from researchers, academicians, engineers, medical scientists, and pharmacists. Eutecticity increases drug dissolution, improves drug penetration, and acts as a synthesis route for drug carriers.Author: Paul W Stott, Adrian C Williams, Brian W Barry
https://www.sciencedirect.com/science/article/pii/S0168365919305565
Drug delivery 2.1. Eutectic mixture. Transdermal delivery of drugs has considerable benefits over conventional therapy, such as improving healing efficiency, ameliorating side effects, and avoiding hepatic first-pass metabolism [3,37]. However, the use of transdermal delivery systems is restricted by the capability of a drug to penetrate the skin .Author: Mohamad Hamdi Zainal-Abidin, Maan Hayyan, Gek Cheng Ngoh, Won Fen Wong, Chung Yeng Looi
https://www.mdpi.com/1420-3049/24/19/3583/pdf
gelatin, using deep eutectic solvents (DES) to form bioplastics, which may have application in drug delivery systems. The e ects of DES content on the thermal and mechanical properties of the material were determined. Zein and soy are globular proteins, which both showed a significant change in the properties by the addition of DES.Author: Wanwan Qu, Riina Häkkinen, Jack Allen, Carmine D'Agostino, Andrew P. Abbott
http://www.eurekaselect.com/60876/article
Keywords:transdermal delivery, skin penetration, enhancer, retarder. Abstract: There is considerable interest in the skin as a site of drug application both for local and systemic effect. However, the skin, in particular the stratum corneum, poses a formidable barrier to drug penetration thereby limiting topical and transdermal bioavailability.Author: Heather A.E. Benson
https://www.researchgate.net/publication/7464223_Transdermal_Drug_Delivery_Penetration_Enhancement_Techniques
Thus, there is a need for transdermal drug delivery systems that can inject the required amount of drug and increase the rate of drug release.
http://path.web.ua.pt/publications/17425247.2019.1604680.pdf
systems, but they can also be designed to present polymerizable moieties. Ultimately these mixtures can be applied in the develop-ment of controlled delivery systems, exerting a triple action: acting as monomers for polymers production, as polymerization media itself and by providing the API for controlled drug delivery.
https://www.researchgate.net/publication/332246646_Deep_eutectic_solvents_comprising_active_pharmaceutical_ingredients_in_the_development_of_drug_delivery_systems
Liquid eutectic system of menthol and camphor has been reported as solvent and co-solvent for some drug delivery systems.
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