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https://www.researchgate.net/publication/7471380_Erythrocyte-based_drug_delivery
Erythrocyte-based drug delivery. The use of a physiological carrier to deliver therapeutics throughout the body to both improve their efficacy while minimising inevitable adverse side effects, is an extremely fascinating perspective.
https://www.tandfonline.com/doi/abs/10.1517/17425247.2.2.311
Dec 19, 2012 · The behaviour of erythrocytes as a delivery system for several classes of molecules (i.e., proteins, including enzymes and peptides, therapeutic agents in the form of nucleotide analogues, glucocorticoid analogues) has been studied extensively as they possess several properties, which make them unique and useful carriers.Author: Luiga Rossi, Sonja Serafini, Francesca Pierigé, Antonella Antonelli, Aurora Cerasi, Alessandra Frate...
https://www.sciencedirect.com/science/article/pii/S147305021730143X
The RBC-based delivery prolongs the circulation time of plasminogen activators, abrogates their undesirable interactions with vascular cells and delivers the drug to the interior of nascent thrombi, enabling, thus, thromboprophylaxis in settings where the risk of thrombosis and bleeding are both high.Author: Vassilis L. Tzounakas, Dimitrios G. Karadimas, Issidora S. Papassideri, Jerard Seghatchian, Marianna...
https://www.pharmatutor.org/articles/information-and-article-on-resealed-erythrocytes-as-drug-carrier
Various types of mammalian erythrocytes have been used for drug delivery, including erythrocytes of mice, cattle, pigs, dogs, sheep, goats, monkeys, chicken, rats, and rabbits. To isolate erythrocytes, blood is collected in heparinized tubes by venipuncture.
https://www.semanticscholar.org/paper/RESEALED-ERYTHROCYTE-DRUG-DELIVERY%3A-A-REVIEW-Deepika-Ram/5c31b87dbc4b3fdfed484aa4d76eaba39a47c992
Among these, the erythrocytes have been the most investigated and have found to possess greater potential in drug delivery. Biopharmaceuticals, therapeutically significant peptides and proteins, nucleic acid-based biological, antigens, anticancer drug and vaccines, are among the recently focused pharmaceuticals for being delivered using carrier erythrocytes.
https://www.thno.org/v09p6885.htm
Erythrocyte-based Nanomedicine in Cancer Drug Delivery Engineered RBCs These natural cells possess unique properties that make them capable of carrying therapeutic agents, improving pharmacokinetics, altering pharmacodynamics, and modulating immune responses.
https://www.sciencedirect.com/science/article/pii/S0169409X07002505
Erythrocyte-based delivery of new and conventional drugs is thus experiencing increasing interests in drug delivery and in managing complex pathologies especially when …Author: F. Pierigè, S. Serafini, L. Rossi, M. Magnani
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