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https://www.sciencedirect.com/science/article/pii/S0169409X01002034
Environment-sensitive hydrogels are ideal candidates for developing self-regulated drug delivery systems. For convenience, environment-sensitive hydrogels are classified based on the type of stimuli in this chapter.Author: Yong Qiu, Kinam Park
https://www.sciencedirect.com/science/article/pii/S0014305719314302
Temperature-sensitive hydrogels serve as attractive drug delivery system platforms for the encapsulation and sustained release of a range of therapeutic agents . Different mechanisms, such as passive diffusion, erosion, and swelling, dictate the release of …Author: Dilshad Qureshi, Suraj Kumar Nayak, Samarendra Maji, Arfat Anis, Doman Kim, Kunal Pal
https://www.sigmaaldrich.com/catalog/papers/11744175
For this reason, either pH-sensitive and/or temperature-sensitive hydrogels can be used for site-specific controlled drug delivery. Hydrogels that are responsive to specific molecules, such as glucose or antigens, can be used as biosensors as well as drug delivery systems.
https://www.researchgate.net/publication/11613021_Environment-Sensitive_Hydrogels_for_Drug_Delivery
Environmentally sensitive hydrogels for drug delivery applications also require biocompatibility. Synthesis of new polymers and crosslinkers with more biocompatibility and better biodegradability would be essential for successful applications.
http://kinampark.com/KPTopics/files/Hydrogels,%20Glucose-sensitive/2001%20Qiu%2C%20Environment-sensitive%20hydrogels%20for%20drug%20delivery.pdf
Hydrogels that are responsive to specific molecules, such as glucose or antigens, can be used as biosensors as well as drug delivery systems. Light-sensitive, pressure-responsive and electro-sensitive hydrogels also have the potential to be used in drug delivery and bioseparation.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482766/
Temperature-sensitive hydrogels are probably the most commonly studied class of environment-sensitive polymer systems in drug delivery research. These hydrogels are able to swell or de-swell as a result of changing in the temperature of the surrounding fluid.
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