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https://www.sciencedirect.com/science/article/pii/S0169409X07003134
Enhancing intestinal drug solubilisation using lipid-based delivery systems ... Effective intestinal colloidal solubilisation may be enhanced (as is often the case during the digestion and subsequent solubilisation of lipid solution formulations) or attenuated (e.g. where the solubilisation capacity of …Author: Christopher John Porter, Colin William Pouton, Jean Cuine, William Neil Charman
https://www.researchgate.net/publication/5693025_Enhancing_intestinal_drug_solubilisation_using_lipid-based_delivery_systems
Enhancing intestinal drug solubilisation using lipid-based delivery systems Article · Literature Review in Advanced Drug Delivery Reviews 60(6):673-91 · April 2008 with 71 Reads
https://www.sciencedirect.com/science/article/abs/pii/S0169409X07003134
Enhancing intestinal drug solubilisation using lipid-based delivery ... This review firstly describes the mechanistic rationale which underpins the use of lipid-based delivery systems to enhance drug solubilisation and briefly reviews the available literature describing increases in oral bioavailability after the administration of lipid ...Author: Christopher John Porter, Colin William Pouton, Jean Cuine, William Neil Charman
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590796/
May 19, 2014 · 2. General Routes of LBDDS. Routes like oral, parenteral, ocular, intranasal, dermal/transdermal, and vaginal can be for the administration of the lipid-based drug delivery systems (LBDDS) [4, 5].However, oral route is the most preferred route because of the properties like noninvasiveness, less expensive, and less prone to side effects, such as injection-site reactions.Author: Kent Jørgensen, Jesper Davidsen, Charlotte Vermehren, Sven Frøkjær, Ole G. Mouritsen
https://research.monash.edu/en/publications/enhancing-intestinal-drug-solubilisation-using-lipid-based-delive
T1 - Enhancing intestinal drug solubilisation using lipid-based delivery systems. AU - Porter, Christopher John. AU - Pouton, Colin William. AU - Cuine, Jean. AU - Charman, William Neil. PY - 2008. Y1 - 2008. N2 - Lipid-based delivery systems are finding increasing application in the oral delivery of poorly water-soluble, lipophilic drugs.Author: Christopher John Porter, Colin William Pouton, Jean Cuine, William Neil Charman
https://www.hindawi.com/journals/jphar/2014/801820/
The principle objective of formulation of lipid-based drugs is to enhance their bioavailability. The use of lipids in drug delivery is no more a new trend now but is still the promising concept. Lipid-based drug delivery systems (LBDDS) are one of the emerging technologies designed to address challenges like the solubility and bioavailability of poorly water-soluble drugs. Lipid-based ...Author: Kent Jørgensen, Jesper Davidsen, Charlotte Vermehren, Sven Frøkjær, Ole G. Mouritsen
https://www.deepdyve.com/lp/elsevier/enhancing-intestinal-drug-solubilisation-using-lipid-based-delivery-qvdt6tcGyi
Mar 17, 2008 · Read "Enhancing intestinal drug solubilisation using lipid-based delivery systems, Advanced Drug Delivery Reviews" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884793/
Using light microscope to observe microstructure formation during lipid digestion, we found the possible relationship between drug release and liquid crystalline formed during the in vitro lipolysis of lipid-based drug delivery systems. These results may improve the understanding of the mechanism behind intestinal lipid digestion and absorption ...Author: Lu Xiao, Tao Yi, Ying Liu, Hua Zhou
https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-014-0039-3
Sep 24, 2014 · Therefore, lipid-based drug delivery systems (such as NLCs and SMEDDS) are more advantageous than the other drug delivery systems (solid dispersion or micronization) for BCS II drugs, due to the multiple absorption enhancement mechanisms. Lipid-based drug delivery systems may be an excellent candidate for oral formulation of insoluble drugs.Author: Tengfei Weng, Tengfei Weng, Jianping Qi, Yi Lu, Kai Wang, Kai Wang, Zhiqiang Tian, Kaili Hu, Zongnin...
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