Endotracheal Tube Drug Delivery

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Intubation Aids Bound Tree

    https://www.boundtree.com/Airway-Oxygen-Delivery/Intubation-Aids/c/27
    The Endotracheal Tube Introducer is a disposable, latex free, sterile and individually wrapped device that can be used with difficult intubations. With markings at 10 cm, 20 cm, 30 cm and 40 cm intervals, the introducer will aid in determining the depth of the ET tube. Features: Blend of high and low density polyethylene for optimal stiffness

Endotracheal tube cuffs filled with lidocaine as a drug ...

    https://www.sciencedirect.com/science/article/pii/S0928098701001191
    Endotracheal tube cuffs filled with lidocaine as a drug delivery system: in vitro and in vivo investigations. ... Abstract. The purpose of this study was to examine if lidocaine diffusion across an endotracheal tube cuff could improve post-operative tolerance, especially sore throat. The in vitro release of lidocaine from tube cuffs filled with ...Author: Gilles Dollo, Jean-Pierre Estebe, Pascal Le Corre, François Chevanne, Claude Ecoffey, Roger Le Verge

Nanocluster Budesonide Formulations Enhance Drug Delivery ...

    https://www.sciencedirect.com/science/article/pii/S0022354915316725
    The pulmonary system is an attractive route for drug delivery because the lungs have a large accessible surface area for treatment. For ventilated patients, an endotracheal tube is required for delivering drugs into the lungs. Such tubes are generally poor conduits for delivering traditional aerosol formulations.Author: Warangkana Pornputtapitak, Nashwa El-gendy, Nashwa El-gendy, Cory Berkland

Endotracheal Tube: Purpose, Procedure, and Complications

    https://www.verywellhealth.com/endotracheal-tube-information-2249093
    The endotracheal tube is then connected to a ventilator, which delivers oxygen to the lungs. The process of inserting the tube is called endotracheal intubation. There are many reasons why an endotracheal tube may be placed, including surgery with a general anesthetic, trauma, or serious illness.

Endotracheal tube cuffs filled with lidocaine as a drug ...

    https://www.researchgate.net/publication/222539097_Endotracheal_tube_cuffs_filled_with_lidocaine_as_a_drug_delivery_system_In_vitro_and_in_vivo_investigations
    Endotracheal tube cuffs filled with lidocaine as a drug delivery system: In vitro and in vivo investigations Article (PDF Available) in European Journal of Pharmaceutical Sciences 13(3):319-323 ...

US5540224A - Drug Delivery port endotracheal tube - Google ...

    https://patents.google.com/patent/US5540224A/en
    The present invention relates to endotracheal tubes used for conducting gases or vapors along the trachea, for example by an anesthesiologist, paramedic or emergency room doctor. In particular, the present invention relates to an improved and novel endotracheal tubes having structure which enables the simultaneous administration of medication to both lungs of the patient.Author: Anne M. Buret, Pam Jablenski, Robert A. Virag

An In Vitro Evaluation of Aerosol Delivery Through ...

    http://rc.rcjournal.com/content/57/7/1066
    Jul 01, 2012 · BACKGROUND: Previous research reporting factors influencing aerosol delivery in intubated patients has been largely focused on the endotracheal tube (ETT) during mechanical ventilation, with little comparative analysis of effect of types of artificial airways and their interfaces on aerosol delivery during spontaneous breathing. The purpose of this study was to compare aerosol …

In vitro assessment of drug delivery through an ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC472804/
    A 200 micrograms budesonide Turbohaler was enclosed in a chamber which allowed it to be inserted into a ventilator circuit. Experiments were performed with a multistage liquid impinger in which drug was drawn through the Turbohaler and endotracheal tube at 60 l/min providing an index of the maximum drug delivery achievable via this route.Author: M. L. Everard, S. G. Devadason, P. N. Le Souëf

Case Study: Endotracheal Tube Redesign Forefront Medical ...

    http://forefrontmedical.com/case-study-endotracheal-tube-redesign/
    Aug 13, 2019 · In 2013, Forefront Medical Technology, a specialty contract manufacturer with a focus in disposable diagnostic, drug delivery and medical device systems, was selected by one of its existing clients to support the development of the single-use portion of new endotracheal tube designed to mitigate the incidence of VAP by maintaining constant ...

Oral endotracheal intubation of rats for intratracheal ...

    https://journals.sagepub.com/doi/pdf/10.1258/0023677011911723
    tracheal damage. Moreover, for endotracheal aerosol drug delivery, large tubes are needed in order to reduce aerosol condensation or deposition on the tube’s walls. This ensures tight contact between the tube and trachea, which avoids loss of air or aerosol during application. A relatively simple intubation can be performed using a very thin ...

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