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https://en.wikipedia.org/wiki/Self-microemulsifying_drug_delivery_system
A self-microemulsifying drug delivery system (SMEDDS) is a drug delivery system that uses a microemulsion achieved by chemical rather than mechanical means. That is, by an intrinsic property of the drug formulation, rather than by special mixing and handling. It employs the familiar ouzo effect displayed by anethole in many anise-flavored liquors.
https://innovareacademics.in/journal/ijpps/Vol3Suppl2/1191.pdf
delivery systems (SEDDSs)‐micro‐emulsifying drug delivery systems (SMEDDSs). Both SEDDSs and SMEDDSs have distinct features associated with improved drug delivery properties. SEDDS formulations can be simple binary systems: lipophilic phase …
https://www.academia.edu/24965569/A_REVIEW_ON_SELF-EMULSIFIED_DRUG_DELIVERY_SYSTEM
Improving oral bioavailability of low poorly water soluble drugs using self-emulsifying drug delivery systems (SEDDS) possess significant potential. Oral bioavailability of hydrophobic drugs can be improved using SEDDS, and appears most promising.
https://www.longdom.org/open-access/selfemulsifying-drug-delivery-systems-sedds-in-pharmaceuticaldevelopment-2090-4568-1000130.pdf
Self-Emulsifying Drug Delivery Systems (SEDDS) SEDDS are defined as a pre-concentrate containing a mixture of drug, oil, surfactant, co-surfactant and, sometimes, co-solvent [18,26-30]. SEDDS is a broad term associated with the production of emulsions with a droplet size ranging from a few nanometers toFile Size: 540KB
http://ijpsr.com/bft-article/self-emulsifying-drug-delivery-system-a-review/?view=fulltext
Self-Micro Emulsifying Drug Delivery System (SMEDDS): SMEDDS are micro-emulsions formed by the SEDDS. It is thermodynamically stable and forms optically transparent emulsion. The major difference between micro-emulsions and common emulsions is mainly due to particle size of droplets.
https://www.researchgate.net/publication/313438437_A_review_on_Self_Emulsifying_Drug_Delivery_System
A self-emulsifying drug delivery system (SEDDS) of a poorly water soluble drug, irbesartan (IRB), was designed. The aim was to improve the solubility as well as dissolution rates of IRB.
http://www.materialsciencejournal.org/vol15no1/development-and-characterization-of-drug-loaded-self-solid-nano-emulsified-drug-delivery-system-for-treatment-of-diabetes/
The aim of present work was the development and characterization of self-solid nano-emulsified drug delivery system (SNEDDS) formulation of embelin in combination with gliclazide for the determination of antidiabetic effect in Wistar rats.Author: Muzamil Rashid, Taha Umair Wani, Neeraj Mishra, Hasham S. Sofi, Roqia Ashraf, Faheem A. Sheikh
https://www.nature.com/articles/srep26895
May 31, 2016 · Lipid-based self-emulsifying drug delivery systems (SEDDS) have attracted the attention of several research groups, due to their potential …Author: Guru R. Valicherla, Guru R. Valicherla, Kandarp M. Dave, Anees A. Syed, Mohammed Riyazuddin, Anand P...
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/self-microemulsifying-drug-delivery-system
These systems are spontaneously emulsified in situ when exposed to gastrointestinal tract (GIT) fluids, forming oil-in-water nanoemulsions with droplet size of 100–250 nm. Self-microemulsifying drug delivery systems (SMEDDS), in comparison, contain a higher content of hydrophilic surfactants and cosurfactants, wherein lipid content is reduced.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674636/
Feb 06, 2015 · SEDDS is a stable mixture of drug, oil, surfactant, and co-surfactant; while self-microemulsifying drug delivery system (SMEDDS) is SEDDS which can form fine oil-in-water droplets with a diameter size of less than 50 nm under mild agitation of the gastrointestinal tract without the dissolution process .Author: Lan Wu, Yanli Qiao, Lina Wang, Jiahua Guo, Guocheng Wang, Wei He, Lifang Yin, Jinhua Zhao
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