Eligen Drug Delivery Technology

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Barriers to Oral Drug Delivery - Emisphere Technologies

    https://emisphere.com/barriers/
    Barriers to Oral Drug Delivery. ... Emisphere's Eligen ® Technology overcomes major obstacles to effective oral delivery including: Degradation. The high acid content and enzymes of the digestive tract can degrade some drugs, particularly protein and peptide drugs, before they are absorbed into the bloodstream. ... Emisphere Technologies 2020 ...

ORAL PEPTIDE DELIVERY: TECHNOLOGY LANDSCAPE & CURRENT ...

    https://www.ondrugdelivery.com/review-oral-peptide-delivery/
    PROTEIN ORAL DELIVERY TECHNOLOGY POD ™ POD technology developed by Oramed (Jerusalem, Israel), consists of enteric-coated capsules containing an oily suspension of the peptide drug, an enzyme inhibitor, such as soy bean trypsin inhibitor, aprotinin and an absorption enhancer such as EDTA or bile salt, in omega-3 fatty acids.

Oral delivery of insulin with the eligen technology ...

    https://www.ncbi.nlm.nih.gov/pubmed/16305420
    The eligen technology employs low molecular weight compounds (termed drug delivery agents or carriers) which interact weakly and non-covalently with insulin, increasing its lipophilicity and thereby its ability to cross the gastrointestinal epithelium. In this study we investigated the mechanism of insulin absorption across caco-2 cell ...Author: Dmitry Malkov, Robert Angelo, Huai-zhen Wang, Elizabeth Flanders, Heather Tang, Isabel Gomez-Orellan...

Drug Delivery Technology RG Journal Impact Rankings 2018 ...

    https://www.researchgate.net/journal/1537-2898_Drug_Delivery_Technology
    Drug Delivery Technology RG Journal Impact: ... and food companies to assess the likelihood of success in combining various nutritional compounds with SNAC or other Eligen carriers. Success in ...

Eligen Technology for Oral Delivery of Proteins and Peptides

    https://www.researchgate.net/publication/278078354_Eligen_Technology_for_Oral_Delivery_of_Proteins_and_Peptides
    The Eligen® technology, an oral delivery technology, is based on the design and development of proprietary delivery carriers referred to as Emisphere delivery agents.

Emisphere Reports Positive Clinical Results for Its Oral ...

    http://ir.emisphere.com/news-releases/news-release-details/emisphere-reports-positive-clinical-results-its-oral-drug
    Such molecules are usually delivered by injection; in many cases, their benefits are limited due to poor bioavailability, slow on-set of action or variable absorption. The Eligen(R) Technology can be applied to the oral route of administration as well other delivery pathways, such as buccal, rectal, inhalation, intra-vaginal or transdermal.

Investor Relations Emisphere Technologies, Inc

    http://ir.emisphere.com/
    Investor Relations Emisphere Technologies is a Drug Delivery Company whose core business strategy is to partner its proprietary drug delivery technology and license Eligen B12. Our thirty year history has made us the established leader in converting injectable therapeutics into advanced oral therapeutics.

Emisphere Provides Development Update on Novo Nordisk Drug ...

    https://drug-dev.com/emisphere-provides-development-update-on-novo-nordisk-drug-using-its-eligen-snac-carrier-technology/
    Emisphere Technologies, Inc. is a drug delivery company that utilizes its proprietary Eligen Technology to develop new oral formulations of therapeutic agents. Emisphere is currently partnered with global pharmaceutical companies for the development of new orally delivered therapeutics. For more information, visit www.emisphere.com.

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