Electroporation Transdermal Drug Delivery

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Electroporation for Dermal and Transdermal Drug Delivery ...

    https://link.springer.com/chapter/10.1007/978-3-662-53273-7_7
    May 05, 2017 · Transdermal drug delivery can offer potential advantages over conventional oral and parenteral drug administration. However, the protective function of skin imposes a physicochemical barrier to the penetration of hydrophilic and large molecules. The …Author: Babu M. Medi, Buddhadev Layek, Jagdish Singh

Perspectives on Transdermal Electroporation

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810085/
    Mar 17, 2016 · Physical approaches for enhancing transdermal drug delivery include sonophoresis [9,10], iontophoresis [11,12,13], MNs [14,15,16,17] and electroporation [18,19]. Physical techniques are sometimes more effective in comparison with chemical enhancers such as low molecular alcohols or aliphatic esters [ 20 ].Author: Kevin B. Ita

Skin electroporation for transdermal and topical delivery ...

    https://www.sciencedirect.com/science/article/pii/S0169409X03002436
    Electroporation is the transitory structural perturbation of lipid bilayer membranes due to the application of high voltage pulses. Its application to the skin has been shown to increase transdermal drug delivery by several orders of magnitude.Author: Anne-Rose Denet, Rita Vanbever, Véronique Préat

Punching and Electroporation for Enhanced Transdermal Drug ...

    https://www.thno.org/v08p3688.htm
    Transdermal drug delivery provides an alternative to oral administration and hypodermic injections to enhance bioavailability, coupled with the advantages of the user-friendly route and improved patient compliance [ 2, 3 ].

Punching and Electroporation for Enhanced Transdermal Drug ...

    https://www.ncbi.nlm.nih.gov/pubmed/30026875
    Jun 08, 2018 · Punching and Electroporation for Enhanced Transdermal Drug Delivery. Yang G(1)(2), Zhang Y(1), Gu Z(1)(3)(4). Author information: (1)Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill, and North Carolina …Author: Guang Yang, Yuqi Zhang, Zhen Gu

Skin Electroporation for Transdermal and Topical Drug Delivery

    https://www.researchgate.net/publication/290802375_Skin_Electroporation_for_Transdermal_and_Topical_Drug_Delivery
    Electroporation is a technique widely used for transdermal delivery. Unlike iontophoresis, which directly drives the drug molecules to move into the skin by electrical repulsion, electroporation...

Skin electroporation for transdermal and topical delivery.

    https://www.ncbi.nlm.nih.gov/pubmed/15019751
    Mar 27, 2004 · Electroporation is the transitory structural perturbation of lipid bilayer membranes due to the application of high voltage pulses. Its application to the skin has been shown to increase transdermal drug delivery by several orders of magnitude.Author: Anne-Rose Denet, Rita Vanbever, Véronique Préat

Electroporation – Advantages and Drawbacks for Delivery of ...

    https://www.intechopen.com/books/application-of-nanotechnology-in-drug-delivery/electroporation-advantages-and-drawbacks-for-delivery-of-drug-gene-and-vaccine
    Skin electroporation could be particularly appropriate for topical drug delivery. Skin electroporation temporarily permeabilizes the barrier to drug permeation and therefore could broaden topical delivery to drugs not suitable for delivery by passive diffusion (i.e., hydrophilic, charged, and/or large molecular drugs).Author: Azam Bolhassani, Afshin Khavari, Zahra Orafa

Electroporation - an overview ScienceDirect Topics

    https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/electroporation
    Inovio's CELLECTRA series of electroporation devices 383 and Ichor's TriGrid delivery system 385 are capable of ID and IM delivery. A hollow needle injects the drug conventionally, while parallel solid needles surrounding the injected dose create the current to generate pores in the target muscle tissue.

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