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https://www.researchgate.net/publication/251251429_Cyclodextrin-Containing_Polymers_for_Gene_Delivery
A common property of all cyclodextrin-containing polymers for nucleic-acid delivery is that they are polycations. One of important feature that is observed with cyclodextrin-contained polycations ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015834/
Oct 24, 2013 · The complex nature of in vivo gene transfer establishes the need for multifunctional delivery vectors capable of meeting these challenges. An additional consideration for clinical translation of synthetic delivery formulations is reproducibility and scale-up of materials. ... Effects of structure of beta-cyclodextrin-containing polymers on gene ...Author: Julie Shi, Joan G Schellinger, Suzie H Pun
http://faculty.washington.edu/spun/pub.php
Optimization of cyclodextrin-polymers specifically designed for gene delivery. Proceedings of the 221st American Chemical Society National Meeting, Polymeric Materials: Science & Engineering 2001, 8, 809-810. Hwang SJ, Bellocq NC, and Davis ME. Effects of structure of beta-cyclodextrin-containing polymers on gene delivery.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242722/
Oct 27, 2014 · Selecting nonviral carriers for in vivo gene delivery is often dependent on determining the optimal carriers from transfection assays in vitro. ... Effects of structure of beta-cyclodextrin-containing polymers on gene delivery. Bioconjug Chem. 2001; 12:280–290.Author: Qixin Leng, Szu-Ting Chou, Puthupparampil V. Scaria, Martin C. Woodle, A. James Mixson
https://www.hindawi.com/journals/jdd/2012/262731/ref/
Nanoparticles are being widely explored as potential therapeutics for numerous applications in medicine and have been shown to significantly improve the circulation, biodistribution, efficacy, and safety profiles of multiple classes of drugs. One leading class of nanoparticles involves the use of linear, cyclodextrin-containing polymers (CDPs).Author: Jeremy D. Heidel, Thomas Schluep
https://link.springer.com/article/10.1007/s41061-017-0112-0
Feb 08, 2017 · As an option for genetic disease treatment and an alternative for traditional cancer chemotherapy, gene therapy achieves significant attention. Nucleic acid delivery, however, remains a main challenge in human gene therapy. Polymer-based delivery systems offer a safer and promising route for therapeutic gene delivery. Over the past five decades, various cationic polymers have been …Author: Peng Zhang, Peng Zhang, Ernst Wagner, Ernst Wagner
https://www.sciencedirect.com/science/article/pii/S0144861713000039
Highlights Tested the β-CD-(D 3) 7 as the vector to transfect the human neuroblastoma SH-SY5Y cells. Exhibited good physicochemical properties of the β-CD-(D 3) 7 /plasmid DNA (pDNA) complexes. Exhibited a low cytotoxicity and efficient pDNA transfection capability in SH-SY5Y cells. β-CD-(D 3) 7 might be a promising candidate for neurotypic cells gene delivery.Author: Bing Liang, Jun Jie Deng, Jun Jie Deng, Fang Yuan, Ning Yang, Wei Li, Jian Rui Yin, Shu Xiang Pu, Lo...
https://www.nature.com/articles/nmat3765
Oct 23, 2013 · Therapeutics based on small interfering RNA (siRNA), which in principle are able to reversibly silence any gene of interest, are under development for the …Author: Rosemary Kanasty, Joseph Robert Dorkin, Arturo Vegas, Arturo Vegas, Daniel Anderson
https://www.researchgate.net/publication/258042387_Engineering_biodegradable_and_multifunctional_peptide-based_polymers_for_gene_delivery
Engineering biodegradable and multifunctional peptide-based polymers for gene delivery Article (PDF Available) in Journal of Biological Engineering 7(1):25 · October 2013 with 171 Reads
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