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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527668/
Although the definition identifies nanoparticles as having dimensions below 0.1 μm or 100 nm, especially in the area of drug delivery relatively large (size >100 nm) nanoparticles may be needed for loading a sufficient amount of drug onto the particles.Author: Wim H De Jong, Paul Ja Borm
https://today.uconn.edu/2017/04/size-matters-drug-particles/
Apr 13, 2017 · “When it comes to using particles for the delivery of cancer drugs, size matters,” Ma says. “When you have a bigger particle, the chance of it bumping into blood cells is much higher, there are a lot more collisions, and they tend to get pushed to the blood vessel walls.” The results were somewhat surprising.
https://pubs.acs.org/doi/abs/10.1021/acs.molpharmaceut.6b00896
Effect of size on the in vitro / in vivo drug release and degradation of exenatide-loaded PLGA microspheres. Journal of Drug Delivery Science and Technology 2018, 45, 346-356. DOI: 10.1016/j.jddst.2018.03.024.Author: Weiluan Chen, Amelia Palazzo, Wim E. Hennink, Robbert J. Kok
https://www.horiba.com/scientific/products/particle-characterization/applications/drug-delivery/
Nanoparticles used for drug delivery is an important research field combining the life sciences with nanotechnology. While the strict definition of a nanoparticle is between 1 – 100 nm, we can extend the upper size range in the context of this application up to approximately 500 nm.
https://bmcsystbiol.biomedcentral.com/articles/10.1186/s12918-017-0491-4
Nov 25, 2017 · Particle size is a key parameter for drug-delivery nanoparticle design. It is believed that the size of a nanoparticle may have important effects on its ability to overcome the transport barriers in biological tissues. Nonetheless, such effects remain poorly understood.Author: Mohammad Aminul Islam, Sutapa Barua, Dipak Barua
https://www.micromeritics.com/Repository/Files/The_Impact_of_Dissolution_on_Particle_Size_and_Particle_Shape_of_Multi-Component_Drug_Delivery_Systems.pdf
The Impact of Dissolution on Particle Size and Particle Shape of Multi-Component Drug Delivery Systems Purpose Background www.micRx.com Micromeritics Pharmaceutical Services 4356 Communications Dr., Norcross, GA 30093, USA [email protected] The particle size and particle shape of multi-component con-
https://www.sciencedirect.com/science/article/pii/S0939641107002895
Polymeric particles used for drug delivery are defined as colloidal systems made of solid polymers . The need for intravenous (IV) formulations and the advantage of enlarging surface contact with an external medium to control release kinetics have encouraged the development of nanoparticles (<1 μm).Author: Marie Gaumet, Angelica Vargas, Robert Gurny, Florence Delie
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