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https://www.sciencedirect.com/science/article/pii/B9780444626141000077
The commonly used preparation method of polymeric nanoparticles needs stabiliser. The stabiliser adsorbs on the surface of polymeric nanoparticles and then generates an electric shielding effect of the charged nanoparticles. That causes diminution of the enhancement effect of IP in the case of transdermal delivery of nanoparticles.Author: Keishiro Tomoda, Kimiko Makino
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733966/
Dec 04, 2017 · Transdermal drug delivery (TDD) has a great advantage over oral administration, which avoids digestion and absorption of the gastrointestinal tract and thus largely reduces drug toxicity and bypasses the first effect of drug absorption, effectively improve the local drug concentration.Author: Nongshan Zhang, Yiyun Wu, Runlin Xing, Bo Xu, Dai Guoliang, Peimin Wang
https://www.sciencedirect.com/science/article/pii/S0378517318308500
The study of nanoparticles (NP) as an efficient drug delivery medium has been in the spotlight for the past few decades (Davoudi et al., 2018, Zheng et al., 2016, Hu et al., 2017, Nguyen et al., 2016).Compared to other modes of transdermal drug delivery systems (TDDS), nanoparticles often show superior drug release, deeper drug penetration, and allow for the encapsulation of both hydrophilic ...Author: Prerana Carter, Balaji Narasimhan, Qun Wang
https://www.tandfonline.com/doi/abs/10.3109/02652049109069563
Sep 18, 2017 · AbstractThe purpose of the present study was to assess by in vitro means the effect of poly (methylmethacrylate) nanoparticles and poly (butylcyanoacrylate) nanoparticles on transdermal drug delivery. Methanol and octanol were chosen as test permeants. In order to distinguish between thermodynamic effect and those due to biological consequences, two different membranes were …Author: Markus J. Cappel, Jörg Kreuter
https://www.intechopen.com/books/application-of-nanotechnology-in-drug-delivery/nanoparticles-for-dermal-and-transdermal-drug-delivery
The term “nanoscale” refers to particle size range from ~ 1 to 100 nm [], but for the purpose of drug delivery, nanoparticles in the range of 50 – 500 nm are acceptable depending on the route of administration.The method by which a drug is delivered can have a significant effect on its efficacy.Author: Okoro Uchechi, John D. N. Ogbonna, Anthony A. Attama
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527668/
A multitude of substances are currently under investigation for the preparation of nanoparticles for drug delivery, varying from biological substances like albumin, gelatine and phospholipids for liposomes, and more substances of a chemical nature like various polymers and solid metal containing nanoparticles.Author: Wim H De Jong, Paul Ja Borm
https://www.hindawi.com/journals/bmri/2017/3273816/
Effect of Ultrasound-Enhanced Transdermal Drug Delivery Efficiency of Nanoparticles and Brucine Nongshan Zhang , 1 Yiyun Wu , 1 Runlin Xing , 1 Bo Xu , 1 Dai Guoliang , 1 and Peimin Wang 1 1 Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, ChinaAuthor: Nongshan Zhang, Yiyun Wu, Runlin Xing, Bo Xu, Dai Guoliang, Peimin Wang
https://link.springer.com/article/10.1007%2Fs12032-009-9192-1
Mar 12, 2009 · Realgar has been used successfully to treat diseases for thousands of years, but its poor water solubility and high toxicity hampered its further medical uses. Here, we first applied transdermal drug delivery system to deliver realgar nanoparticles to investigate its anticancer effect and toxicity in vivo. In this study, MTT assay and flow cytometry analysis demonstrated that realgar ...Author: Qi-Hong Zhao, Ying Zhang, Yun Liu, Hui-Li Wang, Yuan-Yuan Shen, Wen-Jun Yang, Long-Ping Wen
https://www.researchgate.net/publication/49830276_Nanoparticles_and_microparticles_for_skin_drug_delivery
range [19] as topical nanoparticles for drug delivery in skin [20] and both utilize lipids to facilitate payload delivery ( Fig. 2 ). The bene fi ts of drug delivery resulting from topical ...
https://www.researchgate.net/publication/316878494_Docetaxel_loaded_solid_lipid_nanoparticles_A_novel_drug_delivery_system
Docetaxel loaded solid lipid nanoparticles: A novel drug delivery system ... with key emphasis on controlled and site specific drug delivery along with enhanced anti-tumor activity elucidated via ...
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