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https://www.sciencedaily.com/releases/2017/10/171023180627.htm
Oct 23, 2017 · Liposomes are successful drug delivery vehicles prescribed for several types of cancer but also for treatment of fungal infections or pain management. Now researchers from the Medical University of Vienna show a straightforward method to functionalize liposomes for specific targeting, potentially paving the way to personalized medicine.
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/liposomal-drug-delivery
Among many drug delivery systems, liposomal drug delivery is the most extensively investigated in the treatment of topical disorders such as psoriasis, skin cancer, and atopic dermatitis. This delivery approach provides enhanced efficacy and lowered the incidence of side effects as compared with conventional formulations, whereas it also reduces skin irritation, staining, and attribute-controlled …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664963/
Dec 01, 2015 · Biological challenges facing liposomal drug delivery systems. As with any foreign particle that enters the body, liposomes encounter multiple defense systems aimed at recognition, neutralization, and elimination of invading substances. These defenses include the RES, opsonization, and immunogenicity (Willis and Forssen, 1998).Author: Lisa Sercombe, Tejaswi Veerati, Tejaswi Veerati, Fatemeh Moheimani, Sherry Y. Wu, Anil K. Sood, Susa...
https://www.tandfonline.com/doi/abs/10.1080/10717544.2016.1177136?needAccess=true
Liposomes were the first nanoscale drug to be approved for clinical use in 1995. Since then, the technology has grown considerably, and pioneering recent work in liposome-based delivery …Author: Claudia Zylberberg, Sandro Matosevic
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017847/
Apr 14, 2018 · 4. Stability of Liposomes. Physical and chemical stability of the liposomes in terms of size distribution, entrapment efficiency, and minimal degradation of liposomal apparatuses is the major limiting step for drug delivery using this system.Author: Temidayo O. B. Olusanya, Rita Rushdi Haj Ahmad, Daniel M. Ibegbu, James R. Smith, Amal Ali Elkordy
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043431/
Sep 28, 2016 · Endocytosis is the most common pathway for the uptake of small particles including liposomes by cells. To investigate whether endocytosis played a role in the liposomal delivery, the endosome tracker pHrodo, a fluorescently labeled dextran, was used in combination with TOPRO3 loaded liposomes.Author: Jian Yang, Azadeh Bahreman, Geert Daudey, Jeroen Bussmann, René C. L. Olsthoorn, Alexander Kros
https://www.sciencedirect.com/science/article/pii/S0168365918304516
With the use of pp-lipo, effective and on-demand drug delivery has been demonstrated in a sonodynamic-dependent manner both in vitro and in vivo. This drug release via pp-lipo shows good potential for US triggered controlling liposomal drug release and provides a promising platform for the delivery of therapeutics to tumors. Further optimization of US exposure parameters is required to …Author: Xiaobing Wang, Xiaobing Wang, Fei Yan, Xiufang Liu, Pan Wang, Shuai Shao, Yue Sun, Zonghai Sheng, Qu...
https://www.intechopen.com/books/application-of-nanotechnology-in-drug-delivery/liposomes-as-potential-drug-carrier-systems-for-drug-delivery
Structural and design considerations for liposomal drug delivery. Liposomes can be surface functionalized to endow stealth through PEGylation and to promote receptor-mediated endocytosis by using targeting ligands such as antibodies, peptides, proteins, carbohydrates, and …Author: Melis Çağdaş, Ali Demir Sezer, Seyda Bucak
https://www.sciencedirect.com/science/article/pii/S0169409X12002980
Drug release rates have important implications for the therapeutic activities of all types of drug delivery systems, including liposomes. It is important to keep in mind that drug entrapped in liposomes is not bioavailable; it only becomes bioavailable when it is released.Author: Theresa M. Allen, Pieter R. Cullis
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