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https://www.sciencedaily.com/releases/2018/12/181220122606.htm
Dec 20, 2018 · Bacteria-based drug delivery system that outperforms conventional methods Date: December 20, 2018 Source: Virginia Tech Summary: An interdisciplinary team has created a drug delivery system that ...
https://www.nature.com/articles/nature18915
Jul 20, 2016 · On page 81, the authors outline a system in which engineered bacteria acting as drug-delivery vehicles simultaneously break down, releasing an …Author: Shibin Zhou
https://www.nature.com/articles/s41598-017-02591-6
May 23, 2017 · The use of live genetically modified bacteria as delivery vehicles for the in situ delivery of therapeutics has to date relied on the use of specific commensal or food-grade bacteria, typically ...Author: Udo Wegmann, Ana Lucia Carvalho, Ana Lucia Carvalho, Martin Stocks, Simon R. Carding, Simon R. Cardi...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883978/
Nov 11, 2019 · Colorectal Cancer Therapy Using a Pediococcus pentosaceus SL4 Drug Delivery System Secreting Lactic Acid Bacteria-Derived Protein p8. Byung Chull An, Yongku Ryu, Yeo-Sang Yoon, Oksik Choi, Ho Jin Park, Tai Yeub Kim, Song-In Kim, Bong-Kyu Kim, and Myung Jun Chung *Author: Byung Chull An, Yongku Ryu, Yeo-Sang Yoon, Oksik Choi, Ho Jin Park, Tai Yeub Kim, Song-In Kim, Bong-...
https://www.nibib.nih.gov/science-education/science-topics/drug-delivery-systems-getting-drugs-their-targets-controlled-manner
Other NIBIB-funded researchers are developing a system of drug delivery using a type of bacteria that has a two-part navigation system—magnetic and oxygen sensing. They have tested the delivery system in mice, achieving a remarkable success delivering drugs to tumors. The bacteria seek out oxygen-poor zones, which are a feature of tumors.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410909/
Apr 17, 2015 · Several chassis have been used for synthetic drug delivery, including bacteriophage, 1,2 bacteria, bacteria-derived lipid vesicles, 3 and eukaryotic cells. 4 In this review, we focus on the current state of the art in applications with bacterial chassis as we believe this holds much promise for the development of microbiota-derived therapeutics.Author: Jan Claesen, Michael A. Fischbach
https://www.sciencedirect.com/science/article/pii/B9780323477208000018
Chapter 1 - Bacterial polyester nanoparticles for drug delivery. ... (PHAs), are accumulated in the form of nanogranular inclusions in the cells of many bacteria and may serve as carbon and energy reserves. The use of PHA nanoparticles for controlled drug delivery has been shown to be potentially useful. ... Targeting Drug Delivery using Ligand ...Author: Mohsin Shah, Sung C. Yoon
https://www.wipo.int/wipo_magazine/en/2014/04/article_0002.html
Bacteria as a Vehicle for Drug Delivery. August 2014. By Catherine Jewell, Communications Division, WIPO. ActoGeniX, a small Belgian biotech company, is breaking new ground in developing a new class of drugs to treat gastrointestinal, immunological and metabolic diseases (such as Type 1 diabetes) which afflict millions.Established in 2006 as a spin-off from research carried out at the ...
http://sitn.hms.harvard.edu/flash/2017/microbial-physicians-delivering-drugs-bacteria/
Mar 17, 2017 · Bacteria as Drug Factories. Bacteria aren’t newcomers to the drug discovery world. In fact, bacteria are routinely transformed into drug-producing factories using a technique known as recombinant DNA technology, in which DNA from difference species is combined and inserted into a host organism. Take insulin, for example.
https://en.wikipedia.org/wiki/Microbial_drug_delivery
Microbial drug delivery is an emerging form of drug administration characterized by the use of commensal microbes that have been genetically modified to produce medications for chronic diseases in humans. Only proteinaceous drugs can be produced by microbes, as DNA encodes for protein.
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