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https://www.researchgate.net/publication/10566353_Drug_delivery_to_the_lungs_from_dry_powder_inhalers
Drug delivery to the lung from dry powder inhalers is dependent upon the patient's peak inhaled flow rate, and so it is very important to be able to assess the amount and location of drug ...
https://www.ncbi.nlm.nih.gov/pubmed/12974538
In recent years, many dry powder inhalers have been developed by the pharmaceutical industry. Drug delivery to the lung from dry powder inhalers is dependent upon the patient's peak inhaled flow rate, and so it is very important to be able to assess the amount and location of …Author: Stephen P. Newman
https://www.ondrugdelivery.com/dry-powder-inhalers-towards-effective-affordable-sustainable-respiratory-healthcare/
Cruz C et al, “Carrier-based formulation dry powder inhalers using TwinCaps®: aerodynamic particle size distribution and laser diffraction analysis for a typical patient population peak inspiratory flow rate range”. Proc Respiratory Drug Delivery Europe, 2019, pp 277-282.
https://www.sciencedirect.com/topics/neuroscience/dry-powder-inhaler
Yousef Javadzadeh, Shadi Yaqoubi, in Nanostructures for Drug Delivery, 2017. 6.3 Dry Powder Inhaler. Dry powder inhalers (DPI) are the third type of inhaler device that seems to be the most promising devices for future use (Hamishehkar et al., 2012).The breath actuating possibility of these devices is an advanced feature that overcomes the problem of coordination of patient breathing and the ...
https://www.ondrugdelivery.com/selection-excipients-dry-powder-inhalers/
Sim S et al, “An insight into powder entrainment and drug delivery mechanisms from a modified Rotahaler ® ”. Int J Pharm, 2014, Vol 477, pp 351–60. Edwards D, “Applications of capsule dosing techniques for use in dry powder inhalers”. Ther Deliv, 2010, Vol 1, pp 195–201.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733285/
May 30, 2019 · Drug losses in the mouth-throat region are a potential source of variability for inhaled drug delivery to the lungs ... Gjaltema D., Hagedoorn P. Inhalation characteristics and their effects on in vitro drug delivery from dry powder inhalers Part 2: Effect of peak flow rate (PIFR) and inspiration time on the in vitro drug release from three ...Author: Myrna B. Dolovich, Andreas Kuttler, Thomas J. Dimke, Omar S. Usmani
https://www.youtube.com/watch?v=NZhAdV4V1H4
Jul 31, 2015 · Pulmonary Drug Delivery, Hard Capsules and Dry Powder Inhalers: Solving Development Challenges ... of the active ingredient deep into the lungs. ... the mechanics of dry powder inhalers and how ...Author: Xtalks Webinars
https://link.springer.com/10.1007/s11095-016-2050-x
Oct 13, 2016 · Current marketed dry powder inhalers utilize the energy from patient inspiration to fluidize and disperse bulk powder agglomerates into respirable particles. Variations in patient inspiratory flow profiles can lead to marked differences in total lung dose (TLD), and ultimately patient outcomes for an inhaled therapeutic. The present review aims to quantitate the flow rate dependence in TLD ...Author: Jeffry Weers, Andy Clark
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