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https://www.sciencedirect.com/science/article/pii/S0142961217307640
For bone marrow drug delivery, the drug accumulation amounts in the bone are ascribed to the uptake of particulates by phagocytic reticulo-endothelial cells of sinusoid vessels in the bone marrow . The endothelium of vascular sinusoids collects particulates from the blood circulation via both transcellular and intercellular routes.Author: Chao-Feng Mu, Jianliang Shen, Jianliang Shen, Jing Liang, Hang-Sheng Zheng, Yang Xiong, Ying-Hui Wei...
https://pharmawiki.in/ppt-bone-marrow-targeting-and-targeting-to-lysosomal-diseases/
Jan 22, 2014 · January 22, 2014 Kiran Kumar Presentation Comments Off on [PPT] Bone marrow targeting and targeting to lysosomal diseases ← [PPT] Aptamers and anti sense agents [PPT] Clinical pharmacokinetics in pregnancy and lactation →
https://stemcellsjournals.onlinelibrary.wiley.com/doi/full/10.1002/sctm.18-0024
The development of mesenchymal stem cells (MSCs) as cell‐based drug delivery vectors for numerous clinical indications, including cancer, has significant promise. However, a considerable challenge for effective translation of these approaches is the limited tumor tropism and broad biodistribution observed using conventional MSCs, which raises concerns for toxicity to nontarget …
https://www.researchgate.net/publication/299979500_DRUG_DELIVERY_TO_BRAIN_AND_BONE_MARROW_A_REVIEW
drug delivery to brain and bone marrow: a review Rahul Saikia, Ashis Kumar Goswami and Hemanta Kumar Sharma* Department of Pharmaceutical Sciences, Dibrugarh Universit y, …
https://onlinelibrary.wiley.com/doi/pdf/10.1111/os.12238
Bone-targeted drug delivery systems are used to concentrate chemotherapeutic drugs in bone tis- sues, thus potentially resolving the problem of reaching the desired foci and minimizing the toxicity and adverse effects of neoadjuvant chemotherapy. Some progress has been made in bone-targeted drug delivery systems for treat-Author: Cheng‐jun Li, Xiao‐zhou Liu, Lei Zhang, Long‐bang Chen, Xin Shi, Su‐jia Wu, Jian‐ning Zhao
https://digitalcommons.library.tmc.edu/utgsbs_dissertations/158/
E-selectin is constitutively expressed on the bone marrow vasculature, but almost absent in normal vessels, and therefore, E-selectin targeted drug delivery presents an ideal strategy for the delivery of therapeutic nanoparticles to the bone marrow.Author: Aman Mann
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278842/
Liposomal drug delivery can improve the therapeutic index of treatments for multiple myeloma. However, an appropriate 3D model for the in vitro evaluation of liposomal drug delivery is lacking. In this study, we applied a previously developed 3D bone marrow (BM) myeloma model to examine liposomal drug therapy.Author: Maaike V.J. Braham, Anil K. Deshantri, Monique C. Minnema, F. Cumhur Öner, Raymond M. Schiffelers, M...
http://www.authorstream.com/Presentation/karumurychayasree-1523959-bonemarrow-targeting/
Aug 31, 2012 · Colloidal Carriers for Bone Marrow Targeting The ability of the bone marrow to remove the particulate matters from the circulation, opens up an idea for the delivery of therapeutic agents by means of colloidal drug carrier systems such as …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076608/
Liposome technology can provide a drug delivery system with high bone marrow targeting that is mediated by specific phagocytosis in bone marrow. Area covered This review focuses on a bone marrow specific liposome formulation labeled with technetium-99m ( 99m Tc).Author: Keitaro Sou, Beth Goins, Babatunde O. Oyajobi, Bruno L. Travi, William T. Phillips
http://www.powershow.com/view/3be518-MThkY/Bone_marrow_powerpoint_ppt_presentation
Bone marrow Red Yellow Bone Fat Reticulin Haematopoiesis red, white, platelets lymphoid Red cells Men Women Hemoglobin (g/l) 140-180 120-160 Hematocrit (%) 40-52 ... – A free PowerPoint PPT presentation (displayed as a Flash slide show) on PowerShow.com - id: 3be518-MThkY
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