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https://www.sciencedirect.com/science/article/pii/S230750231630056X
Therefore topical delivery through nails also known as transungual drug delivery system came into picture. But transungual delivery had its own challenges. Nail plate is made up of cross linked keratin linkages which impart extensive bonding responsible for hardness of the nail plate.Author: Pradnya Palekar Shanbhag, Urvi Jani
https://www.slideshare.net/konathamtejakumarred/drug-delivery-through-nails
Dec 12, 2016 · drug delivery through nails 1. . DRUG DELIVARY THROUGH NAILS SUBMITTED TO Jawaharlal Nehru Technological University Hyderabad Kukatpally, Hyderabad-500085, Telangana, India Industrial training project submission By P.AMBIKA 13GD1R0020 UNDER THE GUIDANCE OF MR.SUDHEER (Department of pharmacy)
https://www.sciencedirect.com/science/article/abs/pii/S230750231630056X
Therefore topical delivery through nails also known as transungual drug delivery system came into picture. But transungual delivery had its own challenges. Nail plate is made up of cross linked keratin linkages which impart extensive bonding responsible for hardness of the nail plate.Author: Pradnya Palekar Shanbhag, Urvi Jani
https://www.ncbi.nlm.nih.gov/pubmed/26981643
On the other hand, there was no detectable amount of terbinafine found in the nail bed and nail matrix in case of control (passive delivery). These studies show that the iontophoretic drug delivery through hyponychium region to other parts of the nail apparatus could be a potential way of onychomycosis treatment. PMID: 26981643 [Indexed for ...Author: Avadhesh Kushwaha, H. N. Shivakumar, S. Narasimha Murthy
http://www.thepharmajournal.com/vol1Issue11/Issue_jan_2013/1.1.pdf
novel ultrasound-mediated drug delivery system has been developed for treatment of a nail fungal disorder (onychomycosis) by improving delivery to the nail bed using ultrasound to increase the permeability of the nail. The slip-in device consists of ultrasound transducers and drug delivery
http://www.japsonline.com/admin/php/uploads/368_pdf.pdf
The nail lacquer is a new drug delivery system in treatment of nail infections. The major hurdle associated with developing nail lacquers treatment for nail disorders is to deliver the active (antifungal) therapeutically effective concentrations to the site of infection, which is often under nail.File Size: 141KB
http://ijpsr.com/bft-article/nail-as-a-promising-drug-delivery-system-for-controlled-release/?view=fulltext
Nail lacquers as Perungual Drug Delivery System: Nail lacquers (varnish, enamel) have been used as a cosmetic for a very long time to protect nails and for decorative purposes. Conventional nail lacquers generally consist of solvents, film forming polymers, resins, which increase the adhesion of the film to the nail plate, plasticizers, which ...
https://www.future-science.com/doi/full/10.4155/tde-2016-0090
Mar 31, 2017 · Current approach for treating dermatophyte onychomycosis includes both oral and topical administration of antifungal agents. The main challenge for the researchers is to develop formulations with high penetrating power through the nail unit allowing delivery of effective drug levels to the site(s) of nail …Author: Ashok K Tiwary, Bharti Sapra
https://www.ncbi.nlm.nih.gov/pubmed/19941943
Feb 15, 2010 · Topical therapies for nail diseases are limited by keratinized cells in the human nail plate. An optimal permeation enhancer would not only improve drug delivery through the nail plate, but would also open new possibilities for treating neighboring target sites if systemic circulation is reached.Author: Ivana Vejnovic, Linda Simmler, Gabriele Betz
https://phys.org/news/2015-06-insight-pharmaceutical-solvents-diffuse-human.html
Jun 19, 2015 · (Phys.org)—One of the biggest difficulties in treating nail disease is finding a topical drug that adequately penetrates through the nail. While some improvements in nail drug delivery have been ...
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