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http://jpet.aspetjournals.org/content/370/3/593
Sep 01, 2019 · Nose-to-Brain Mechanism of Delivery. For the purposes of drug delivery, the nasal cavity is divided into the respiratory area and the olfactory area, with the latter situated high up in the nares and the former closer to the nostrils (Sahin-Yilmaz and Naclerio, 2011).The nasal epithelium is well vascularized (Sahin-Yilmaz and Naclerio, 2011), and, within the olfactory area, olfactory neurons ...Author: Zian Wang, Guojun Xiong, Wai Chun Tsang, Andreas G. Schätzlein, Ijeoma F. Uchegbu
https://www.ncbi.nlm.nih.gov/pubmed/23016642
Drug delivery systems from nose to brain. ... the conventional and novel intranasal drug delivery systems, the various intranasal drug delivery techniques and devices, and examples of brain drug transport that have been feasible in treating various brain disorders. Moreover, products on the market, investigational drugs, and the author's ...Author: Ambikanandan Misra, Gitanjali Kher
http://www.eurekaselect.com/103506/article
The review discusses the potential of intranasal route to deliver drugs to the brain, the mechanisms and pathways of direct nose to brain drug transport, the various factors influencing transnasal drug absorption, the conventional and novel intranasal drug delivery systems, the various intranasal drug delivery techniques and devices, and ...
https://www.ncbi.nlm.nih.gov/pubmed/26996366
RESULTS: The works that are discussed in this paper show better drug targeting of brain when given through nasal route as nanoparticles. Experiments performed in animal models have clearly exhibited that nano-sized formulations are able to facilitate the delivery of drugs to brain through nose in comparison to tantamount drug solutions.Author: Kunjan Phukan, Marika Nandy, Rupanjali B. Sharma, Hemanta K. Sharma
https://www.youtube.com/watch?v=Cuzs-lwmfEs
Feb 08, 2017 · It is direct pathway for transport of drug nose to brain by passing BBB. ... Nose to Brain Drug Delivery System Sagar Savale. ... Increasing drug delivery through the blood-brain barrier ...Author: Sagar Savale
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