Drug Delivery Strategy Utilizing Conjugation

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Drug delivery strategy utilizing conjugation via ...

    https://www.sciencedirect.com/science/article/pii/S0169409X02001795
    Studies on toxin conjugates using disulfide bonds were published as early as the late 1970s , , , and ever since the disulfide-based bioconjugation approach has been a popular conjugation method applied in a variety of cellular drug delivery systems. Successful applications of thiol-based conjugation have obtained targeted delivery and enhanced cytosolic delivery, improved pharmacokinetics and …Author: Go Saito, Joel A. Swanson, Kyung Dall Lee

Drug delivery strategy utilizing conjugation via ...

    https://www.sciencedirect.com/science/article/abs/pii/S0169409X02001795
    Drug delivery strategy utilizing conjugation via reversible disulfide linkages: role and site of cellular reducing activities Author links open overlay panel Go Saito a c Joel A Swanson b Kyung-Dall Lee aAuthor: Go Saito, Joel A. Swanson, Kyung Dall Lee

Drug delivery strategy utilizing conjugation via ...

    https://www.researchgate.net/publication/10919475_Drug_delivery_strategy_utilizing_conjugation_via_reversible_disulfide_linkages_Role_and_site_of_cellular_reducing_activities
    Drug delivery strategy utilizing conjugation via reversible disulfide linkages: Role and site of cellular reducing activities

Lipid Drug Conjugate for Enhancing Drug Delivery

    http://kinampark.com/DDSRef/files/Irby%202017%2C%20Lipid-drug%20conjugate%20for%20enhanced%20drug%20delivery.pdf
    2. CONJUGATION STRATEGIES 2.1. Conjugate Drugs with Fatty Acids. Fatty acids contain a hydrocarbon chain and a reactive carboxylic acid. The commonly used strategy is to conjugate the lipid’s carboxyl end with a hydroxyl or amine group of the drug to form a stable ester or amide linkage (Figure 1). Numerous fatty acids and

Drug delivery strategy utilizing conjugation ... - DeepDyve

    https://www.deepdyve.com/lp/elsevier/drug-delivery-strategy-utilizing-conjugation-via-reversible-disulfide-U8bqFMQnaI
    Feb 10, 2003 · Read "Drug delivery strategy utilizing conjugation via reversible disulfide linkages: role and site of cellular reducing activities, Advanced Drug Delivery Reviews" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at …

Design of zein conjugation and surface modification for ...

    https://www.ncbi.nlm.nih.gov/pubmed/31518220
    Sep 13, 2019 · Diverse strategies for the use of zein for controlled drug release have been investigated and reported in the literature, especially engineering strategies for using zein conjugates to enhance oral bioavailability and targeted delivery, which has attracted interest in recent research.Author: Phuong H-Lien Tran, Thao Truong-Dinh Tran

Drug–Lipid Conjugates for Enhanced Oral Drug Delivery ...

    https://www.researchgate.net/publication/330152162_Drug-Lipid_Conjugates_for_Enhanced_Oral_Drug_Delivery
    Designing of drug–lipid conjugates (DLCs) is one of the rationale strategy utilised in overcoming this challenge. This review extensively covers the various dimensions of drug modification using...

Antibody-drug conjugates: recent advances in conjugation ...

    https://paperity.org/p/78159354/antibody-drug-conjugates-recent-advances-in-conjugation-and-linker-chemistries
    Cancer Res 71 : 2250 - 2259 Saito G , Swanson JA , Lee K-D ( 2003 ) Drug delivery strategy utilizing conjugation via reversible disulfide linkages: role and site of cellular reducing activities . Adv Drug Deliv Rev 55 : 199 - 215 Sedlacek HH , Seemann G , Hoffmann D , Czech J …Author: Kyoji Tsuchikama, Zhiqiang An

Strategies and challenges for the next generation of ...

    https://www.nature.com/articles/nrd.2016.268
    Mar 17, 2017 · Antibody–drug conjugate (ADCs), which aim to target highly cytotoxic drugs specifically to cancer cells, are one of the fastest growing classes …Author: Alain Beck, Liliane Goetsch, Charles Dumontet, Charles Dumontet, Nathalie Corvaïa

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