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https://www.webmd.com/pain-management/guide/spinal-drug-delivery-systems
Pain relief through spinal drug delivery systems, also called intrathecal drug delivery systems, involves implanting a small pump or using a catheter that delivers medication directly to the spinal cord, where pain signals travel. In many cases, spinal drug delivery systems are used to treat people who have cancer pain.
https://neuromodulation.org/Portals/0/For%20Patients%20Education%20Page/Spinal%20Drug%20Delivery%20Systems.pdf
Spinal Drug Delivery Systems A spinal drug delivery system infuses medicines directly into the spinal fluid and to the spinal cord. Cells that have a big influence on the perception of pain are located in the spinal cord, and this direct delivery can have a very potent …
https://www.ncbi.nlm.nih.gov/pubmed/29404792
Feb 05, 2018 · There are new intrathecal drugs under investigation including various conopeptides and AYX1. Large, prospective, modern, randomized controlled studies are still needed to support the use of both intrathecal drug delivery systems as well as spinal cord stimulation for cancer pain populations.Author: Fangfang Xing, R. Jason Yong, Alan David Kaye, Richard D. Urman
https://www.sciencedirect.com/science/article/pii/S0168365911011515
Moreover, in vitro, in vivo and ex vivo drug delivery experiments allowed to fully understand drug diffusion kinetics together with their distribution along the spinal cord and finally also evidenced the key role of CSF convection. In addition, the ability to load multiple drugs allows a single placing procedure, thus reducing surgical risks of further interventions.Author: Giuseppe Perale, Giuseppe Perale, Giuseppe Perale, Filippo Rossi, Filippo Rossi, Marco Santoro, Marc...
http://www.smafoundation.org/wp-content/uploads/2012/03/spinal-cord.pdf
• The blood brain barrier protects the spinal cord by only allowing certain molecules to reach the spinal cord tissue from the blood. • Some drugs are able to cross the blood brain barrier. • For molecules that are unable to penetrate the blood brain barrier, direct delivery to the spinal cord …File Size: 1MB
https://www.clinicalpainadvisor.com/home/topics/cancer-pain/intrathecal-drug-delivery-and-spinal-cord-stimulation-for-cancer-pain-a-review/
Apr 24, 2018 · Intrathecal drug delivery systems and spinal cord stimulation have shown promise for the treatment of cancer pain in initial studies.
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