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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527668/
The non restricted (cyto)toxicity of chemotherapeutics thus limits the full use of their therapeutic potential. Local drug delivery or drug targeting results in increased local drug concentrations and provides strategies for more specific therapy. Nanoparticles have specific particles as …Author: Wim H De Jong, Paul Ja Borm
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386009/
Mar 31, 2015 · Pulmonary drug delivery possesses many advantages, including non-invasive route of administration, low metabolic activity, control environment for systemic absorption and avoids first bypass metabolism. However, because the lung is one of the major ports of entry, it has multiple clearance mechanisms, which prevent foreign particles from ...Author: Ibrahim M. El-Sherbiny, Nancy M. El-Baz, Magdi H. Yacoub
https://www.sciencedirect.com/science/article/pii/S0142961217300704
Exploring deformable particles in vascular-targeted drug delivery: Softer is only sometimes better ... Briefly, female mice (3–4 weeks) were anesthetized and a tail vein catheter placed for delivery of particles. A midline incision in the abdominal cavity allowed for exteriorization of the mouse intestines, and therefore, the mesentery ...Author: Margaret B. Fish, Catherine A. Fromen, Genesis Lopez-Cazares, Alexander W. Golinski, Timothy F. Scot...
https://today.uconn.edu/2017/04/size-matters-drug-particles/
Apr 13, 2017 · The research team also determined that 2 microns was the largest size that should be used if particles are going to have any chance of going through the leaky blood vessel walls into the tumor site. “When it comes to using particles for the delivery of cancer drugs, size matters,” Ma says.
https://www.nature.com/articles/s41591-020-0787-6
Mar 09, 2020 · Drug delivery to the skin is highly constrained by the stratum corneum barrier layer1. Here, we developed star-shaped particles, termed STAR particles, to …Author: Andrew R. Tadros, Andrey Romanyuk, Ian C. Miller, Andrea Santiago, Richard K. Noel, Laura O’Farrell,...
https://lubrizolcdmo.com/technical-briefs/cubic-phase-particles/
Jan 21, 2020 · While these may seem daunting, there are common fundamental properties that drive real-world possibilities. Compounding the difficulty in establishing a decision tree is the fact that there is a myriad of drug delivery approaches being touted by industry players.
https://drug-dev.com/nanoparticles-a-revolution-in-the-development-of-drug-delivery-vehicles/
The versatility of the NanoAssemblr technology means that it can also be applied to a variety of nanoparticle systems – liposomes, lipid nanoparticles, polymer particles, and micelles – offering research and development scientists the flexibility to explore a wide range of drug delivery mechanisms.
https://www.sciencedirect.com/science/article/pii/S0169409X12000087
New nanocarrier platforms based on natural biological building blocks offer great promises in revolutionalizing medicine. The usage of specific protein cage structures: virus-like particles (VLPs) for drug packaging and targetted delivery is summarized here.Author: Y. Ma, Y. Ma, R.J.M. Nolte, Jeroen Johannes Lambertus Maria Cornelissen
https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-018-0392-8
Sep 19, 2018 · Nanotechnology is shown to bridge the barrier of biological and physical sciences by applying nanostructures and nanophases at various fields of science ; specially in nanomedicine and nano based drug delivery systems, where such particles are of major interest [12, 13].Author: Jayanta Kumar Patra, Gitishree Das, Leonardo Fernandes Fraceto, Leonardo Fernandes Fraceto, Estefani...
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