We have collected information about Drug Delivery Of Oligonucleotides By Peptides for you. Follow the links to find out details on Drug Delivery Of Oligonucleotides By Peptides.
https://www.sciencedirect.com/science/article/pii/S0939641104001134
PLL attracted much interest for a variety of (bio)medical applications like gene carriers and drug delivery systems for oligonucleotides. PLL could be synthesised by various synthesis-strategies with different molecular weight (typical 1000 up to >300,000 Da), in linear conformation or as dendritic polypeptides , .A disadvantage is the significant cytotoxicity of the polypeptides depending on ...Author: Dirk Lochmann, Edith Jauk, Andreas Zimmer
https://www.sciencedirect.com/science/article/abs/pii/S0939641104001134
Here, DNA sequences, which facilitate intracellular trafficking of macromolecules to the nucleus were explored. Summarizing the present literature, peptides are interesting pharmaceutical excipients and it seems to be feasible to combine the specific properties of peptides to improve drug delivery devices for oligonucleotides in the future.Author: Dirk Lochmann, Edith Jauk, Andreas Zimmer
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.324.7846
Here, DNA sequences, which facilitate intracellular trafficking of macromolecules to the nucleus were explored. Summarizing the present literature, peptides are interesting pharmaceutical excipients and it seems to be feasible to combine the specific properties of peptides to improve drug delivery devices for oligonucleotides in the future.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6248909/
Apr 16, 2018 · The bicyclic peptides exhibited increased proteolytic stability relative to the monocycle, demonstrating that perfluoroaryl bicyclic peptides are potent and stable delivery agents. Exon-skipping antisense oligonucleotides are effective treatments for genetic diseases, yet exon-skipping activity requires that these macromolecules reach the nucleus.Author: Justin M. Wolfe, Colin M. Fadzen, Rebecca L. Holden, Monica Yao, Gunnar J. Hanson, Bradley L. Pentel...
https://informaconnect.com/peptides-oligonucleotides/articles/
Drug Delivery of Oligonucleotides, Peptides, RNA, mRNA and CRISPR - WHITEPAPER. This whitepaper explores the latest innovations, strategies and challenges of drug delivery of oligonucleotides, peptides, RNA, mRNA and CRISPR. Download it here. European Pharmaceutical Oligonucleotide Consortium.
https://informaconnect.com/peptides-oligonucleotides/
Peptides and Oligonucleotides Drug delivery trends in oligo, peptide, mRNA and CRISPR therapeutics Peptides What are peptides? SPONSORSHIP & EXHIBITION OPPORTUNITIES. There are many ways for your organisation to engage a qualified audience of 40,000+ TIDES executives and scientists, including 2,000+ annual attendees gathered across the globe ...
https://www.researchgate.net/publication/8414049_Drug_delivery_of_oligonucleotides_by_peptides_Eur_J_Pharm_Biopharm_58_237-251
The formulation of these substances were widely studied in the past. With this review we will focus on peptides used as drug delivery vehicles for oligonucleotides. Different strategies are ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390225/
Jun 12, 2012 · There are two main ways of utilizing peptide vectors for the delivery of antisense oligonucleotides and siRNA. The first method involves chemical synthesis of peptides that are modified to enable covalent conjugation to oligonucleotides or other cargo types (Figure 3a). Such conjugation reactions may be carried out either on solid support or in ...Author: Peter Järver, Thibault Coursindel, Samir El Andaloussi, Samir El Andaloussi, Caroline Godfrey, Matth...
https://drugdiscoveryalliances.com/peptides-oligonucleotides-carbohydrates-synthetic-lipids/
Peptides, Oligonucleotides, Carbohydrates and Synthetic Lipids Offering access to a wide range of products, including conjugates, to meet customer needs, including: Fully integrated service offering > from APIs to finished dosage and pharmaceutical services (clinical trial …
Searching for Drug Delivery Of Oligonucleotides By Peptides?
You can just click the links above. The data is collected for you.
