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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527668/
A multitude of substances are currently under investigation for the preparation of nanoparticles for drug delivery, varying from biological substances like albumin, gelatine and phospholipids for liposomes, and more substances of a chemical nature like various polymers and solid metal containing nanoparticles.Author: Wim H De Jong, Paul Ja Borm
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249419/
Thus, the advantages of using nanoparticles for drug delivery are a result of two main basic properties: small size and use of biodegradable materials. Nanoparticles, because of their small size, can extravasate through the endothelium in inflammatory sites, epithelium (e.g., intestinal tract and liver), tumors, or penetrate microcapillaries.Author: Rajesh Singh, James W. Lillard, James W. Lillard
https://www.sciencedirect.com/science/article/pii/S1319016417301792
An ideal nanoparticle drug delivery system should be able to reach, recognized, bind and deliver its load to specific pathologic tissues, and minimize or avoids drug induced damage to healthy tissues.Thus, coating specific targeting ligand(s) on the surface of nanoparticles is the most common strategy.Author: Syed A.A. Rizvi, Ayman M. Saleh
https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-018-0392-8
Sep 19, 2018 · The green chemistry route of designing nanoparticles loaded with drugs is widely encouraged as it minimises the hazardous constituents in the biosynthetic process. Thus, using green nanoparticles for drug delivery can lessen the side-effects of the medications . Moreover, adjustments in nanostructures size, shape, hydrophobicity, and surface ...Author: Jayanta Kumar Patra, Gitishree Das, Leonardo Fernandes Fraceto, Leonardo Fernandes Fraceto, Estefani...
https://www.sciencedirect.com/science/article/abs/pii/S1734114012709015
Cell-specific targeting can be accomplished by attaching drugs to specially designed carriers. Various nanostructures, including liposomes, polymers, dendrimers, silicon or carbon materials, and magnetic nanoparticles, have been tested as carriers in drug delivery systems.Author: Agnieszka Z. Wilczewska, Katarzyna Niemirowicz, Karolina H. Markiewicz, Halina Car
https://www.understandingnano.com/nanotechnology-drug-delivery.html
Perhaps the most publicized use of nanotechnology in drug delivery under development is the use of nanoparticles to deliver drugs to cancer cells. Particles are engineered so that they are attracted to diseased cells, which allows direct treatment of those cells.
https://drug-dev.com/nanoparticles-a-revolution-in-the-development-of-drug-delivery-vehicles/
Nanoparticles, and liposomes in particular, have been used for drug delivery in cancer and inflammatory disease therapies for several years, but traditional manufacturing methods are labor intensive, hard to reproduce, and difficult to scale up.
https://pubs.acs.org/doi/abs/10.1021/acs.iecr.9b04747
Significant efforts have been made to fabricate drug-loaded nanoparticles for drug delivery. Nanoprecipitation is a simple and versatile method for making various types of polymer nanoparticles with well-controlled particle size, size distribution, and surface properties. This review presents a critical overview of three different widely used nanoprecipitation techniques, namely, traditional ...Author: Yun Liu, Guangze Yang, Da Zou, Yue Hui, Krishna D. P. Nigam, Anton Middelberg, Chun-Xia Zhao
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