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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527668/
A multitude of substances are currently under investigation for the preparation of nanoparticles for drug delivery, varying from biological substances like albumin, gelatine and phospholipids for liposomes, and more substances of a chemical nature like various polymers and solid metal containing nanoparticles.Author: Wim H De Jong, Paul Ja Borm
https://news.harvard.edu/gazette/story/2012/04/size-matters-in-drug-delivery/
Apr 11, 2012 · Size matters in drug delivery. ... Few of the large nanoparticles are visible in the bottom left panel, while the smaller nanoparticles have penetrated well, as seen in the bottom right panel. Courtesy of Vikash Chauhan/Nature Nanotechnology. Tumor study reveals size limitations for new drugs.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249419/
Thus, the advantages of using nanoparticles for drug delivery are a result of two main basic properties: small size and use of biodegradable materials. Nanoparticles, because of their small size, can extravasate through the endothelium in inflammatory sites, epithelium (e.g., intestinal tract and liver), tumors, or penetrate microcapillaries.Author: Rajesh Singh, James W. Lillard, James W. Lillard
https://www.sciencedirect.com/science/article/pii/S1319016417301792
An ideal nanoparticle drug delivery system should be able to reach, recognized, bind and deliver its load to specific pathologic tissues, and minimize or avoids drug induced damage to healthy tissues.Thus, coating specific targeting ligand(s) on the surface of nanoparticles is the most common strategy.Author: Syed A.A. Rizvi, Ayman M. Saleh
https://www.prnewswire.com/news-releases/global-200-billion-opportunity-for-nanoparticle-drug-delivery-market-by-2024---size-current-trends-and-dynamics-300633653.html
Global $200 Billion Opportunity for Nanoparticle Drug Delivery Market by 2024 - Size, Current Trends, and Dynamics ... 11.2 Scientific & Technical Limitation Related to Nanoparticles Drug Delivery
https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-018-0392-8
Sep 19, 2018 · The green chemistry route of designing nanoparticles loaded with drugs is widely encouraged as it minimises the hazardous constituents in the biosynthetic process. Thus, using green nanoparticles for drug delivery can lessen the side-effects of the medications . Moreover, adjustments in nanostructures size, shape, hydrophobicity, and surface ...Author: Jayanta Kumar Patra, Gitishree Das, Leonardo Fernandes Fraceto, Leonardo Fernandes Fraceto, Estefani...
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/nanoparticle
Further, nanoparticles from polymers can be prepared by different approaches including solvent evaporation, salting-out, thermal denaturation, dialysis and supercritical fluid technology. This chapter outlines the different strategies for the preparation of polymeric nanoparticles employed for …
https://www.understandingnano.com/nanotechnology-drug-delivery.html
Perhaps the most publicized use of nanotechnology in drug delivery under development is the use of nanoparticles to deliver drugs to cancer cells. Particles are engineered so that they are attracted to diseased cells, which allows direct treatment of those cells.
https://link.springer.com/article/10.1007%2Fs10856-013-4994-2
Jun 25, 2013 · After the first day, 19, 20, 25, and 36 % of the CPT was released from PDA nanoparticles synthesized at pH values of 7.5, 8, 8.5, and 9, respectively, depending on the particle size. The PDA nanoparticles had excellent haemocompatibility: there was no apparent hemolysis, and they did not cause acute toxicity in A549 and HeLa cells.Author: Chia-Che Ho, Shinn-Jyh Ding
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