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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826320/
Oct 28, 2013 · 2. Morphological Study of Liver . Before discussing the different methods of targeting, it is necessary to understand the morphology of liver (especially vascular supply) and molecular scale of the target tissue in order to design a novel drug delivery system rationally.Author: Nidhi Mishra, Narayan Prasad Yadav, Vineet Kumar Rai, Priyam Sinha, Kuldeep Singh Yadav, Sanyog Jain...
https://www.ncbi.nlm.nih.gov/pubmed/31734169
Nov 14, 2019 · Using selected examples of liver cancer, hepatitis B viral infection, fatty liver diseases, and drug-induced liver injury, we highlight efforts made for the sequential delivery of small and macromolecular drugs through different biomaterials, cells, and microdevice-based delivery platforms that allow fast delivery kinetics and rapid drug switching.Author: Xiaozhong Huang, Xiaozhong Huang, Fan Lee, Yao Teng, Yao Teng, Corey Bryen Lingam, Zijian Chen, Ziji...
http://ijpsr.com/bft-article/liver-specific-drug-targeting-strategies-a-review/?view=fulltext
ABSTRACT: Drug delivery to liver is one of the most challenging research areas in pharmaceutical sciences.The some physiological barrier such as opsonization, mechanical entrapment by pulmonary vascular bed, uptake by RES represents an insurmountable obstacle for a large number of proteins and drugs, including antibiotics, antineoplastic agents and antiviral agents to target liver disorders.
https://www.sciencedirect.com/science/article/abs/pii/S0169409X19301929
Using selected examples of liver cancer, hepatitis B viral infection, fatty liver diseases, and drug-induced liver injury, we highlight efforts made for the sequential delivery of small and macromolecular drugs through different biomaterials, cells, and microdevice-based delivery platforms that allow fast delivery kinetics and rapid drug switching.Author: Xiaozhong Huang, Xiaozhong Huang, Fan Lee, Yao Teng, Yao Teng, Corey Bryen Lingam, Zijian Chen, Ziji...
https://www.sciencedirect.com/science/article/pii/S0169409X19301929
Drug delivery systems such as hydrogels, micro/nanoparticles, layer-by-layer (LbL) assembly, and microdevices, as well as a combination of these systems, are potential candidates for sequential drug delivery in liver disease treatment. Hydrogels are physically or chemically cross-linked polymeric networks that can imbibe a large amount of water.Author: Xiaozhong Huang, Xiaozhong Huang, Fan Lee, Yao Teng, Yao Teng, Corey Bryen Lingam, Zijian Chen, Ziji...
https://www.medscape.com/viewarticle/899089
Sep 25, 2019 · "This is the first-in-human and proof-of-principle study to show that drug delivery can be enhanced at the site where it is required by heating the tissue with focused ultrasound to activate the ...
https://www.tandfonline.com/toc/idrd20/current
A peer-reviewed, open access journal providing the academic and industrial communities with coverage of basic research, development, and application principles of drug delivery and targeting at molecular, cellular, and higher levels.
https://clincancerres.aacrjournals.org/content/12/8/2563
Apr 15, 2006 · Background: In the fight against cancer, new drug delivery systems are attractive to improve drug targeting of tumors, maximize drug potency, and minimize systemic toxicity. We studied a new drug delivery system comprising microspheres, with unique properties allowing delivery of large amounts of drugs to tumors for a prolonged time, thereby decreasing plasma levels. Liver tumors, …Author: Kelvin Hong, Afsheen Khwaja, Eleni A Liapi, Michael S. Torbenson, Christos S Georgiades, Jean Franco...
https://www.drugs.com/condition/liver-disease.html
About Liver Disease: The term "liver disease" can apply to many diseases and disorders that cause the liver to function improperly or cease functioning.Abnormal results of liver function tests often suggest liver …
https://www.nature.com/articles/s41467-018-04791-8
Jun 15, 2018 · RNA delivery for disease treatment often has low uptake efficiencies and cytotoxicity. Here the authors produce extracellular vesicles from red blood cells for in vivo cargo delivery.Author: Waqas Muhammad Usman, Tin Chanh Pham, Yuk Yan Kwok, Luyen Tien Vu, Victor Ma, Boya Peng, Yuen San Ch...
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