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https://www.researchgate.net/publication/7471384_Drug_delivery_into_the_brain_using_polylactide-co-glycolide_microspheres
Among the strategies developed for drug delivery into the CNS, locally controlled drug release by the way of an implantable polymeric device has been developed in recent years.
https://www.sciencedirect.com/topics/neuroscience/microsphere
24.5 Microspheres. Microsphere brachytherapy using the beta emission of 90 Y is used in the treatment of ... Upon injecting these microspheres into an artery that supplies a tumor site and magnetically localizing at the capillary level, they act as a time-release capsule system. ... Targeted nose-to-brain drug delivery is achieved by surface ...
https://www.researchgate.net/publication/10644676_Release_of_paclitaxel_from_polylactide-co-glycolide_PLGA_microparticles_and_discs_under_irradiation
Supercritical gas foaming using CO₂ was used to fabricate blank poly DL lactide-co-glycolide (PLGA) micro-porous foams. Paclitaxel-loaded PLGA foams were also produced for the first time using a ...
https://www.sciencedirect.com/science/article/pii/S016836599800056X
Haloperidol-loaded biodegradable poly(d, l-lactide-co-glycolide) (PLG) microspheres, with theoretical mean particle sizes of about 0.8, 2 and 8 μm, have been successfully prepared by using an emulsification–solvent evaporation method.The effect of various processing parameters such as the content of polymer in dichloromethane, the content of polyvinyl alcohol in the aqueous phase, and the ...Author: Yu-Hui Cheng, L Illum, S.S Davis
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124394/
May 27, 2011 · Nanoparticle-based drug delivery systems have many advantages for anticancer drug delivery, including an ability to pass through the smallest capillary vessels, because of their very small volume, and being able to avoid rapid clearance by phagocytes, so that their presence in the blood stream is greatly prolonged.90 Nanoparticles can also ...Author: R Dinarvand, N Sepehri, S Manoochehri, H Rouhani, F Atyabi
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218576/
Oct 28, 2011 · Biodegradable nanoparticles have been extensively investigated in drug delivery systems.16–18 Due to their small particle size, they are attracted to their target tissues and have the advantages of targeted drug delivery to the desired site of action, prolonged blood circulation of the encapsulated drug, and reduced drug side effects.19–21 ...Author: Tae-Ho Kim, Young-Il Jeong, Shu-Guang Jin, Jian Pei, Tae-Young Jung, Kyung-Sub Moon, In-Young Kim, S...
https://www.dovepress.com/development-and-in-vitro-characterization-of-polylactide-co-glycolide--peer-reviewed-article-DDDT
The PLGA microspheres characterized by slow release of totarol and great entrapment efficiency represent a novel drug delivery system, which may be highly beneficial for the long-term therapy of bacterial infections. Keywords: totarol, drug delivery system, …Author: Jochen Reinbold, Teresa Hierlemann, Helena Hinkel, Ingrid Müller, Martin E Maier, Tobias Weindl, Chr...
https://www.drugs.com/pro/vivitrol.html
Vivitrol microspheres consist of a sterile, off-white to light tan powder that is available in a dosage strength of 380-mg naltrexone per vial. Naltrexone is incorporated in 75:25 polylactide-co-glycolide (PLG) at a concentration of 337 mg of naltrexone per gram of microspheres. The diluent is a …8/10
https://www.dovepress.com/development-and-in-vitro-characterization-of-polylactide-co-glycolide--peer-reviewed-fulltext-article-DDDT
The PLGA microspheres characterized by slow release of totarol and great entrapment efficiency represent a novel drug delivery system, which may be highly beneficial for the long-term therapy of bacterial infections. Keywords: totarol, drug delivery system, …Author: Jochen Reinbold, Teresa Hierlemann, Helena Hinkel, Ingrid Müller, Martin E Maier, Tobias Weindl, Chr...
https://researchportal.bath.ac.uk/en/publications/comparison-of-drug-release-from-polylactide-co-glycolide-microsph
The drug loading of cisplatin containing microspheres produced elsewhere is 3 10 {\%}w. Similar microspheres are reported here with a mean diameter of 38.8 μm, and a drug loading of 11.7 {\%}w, but using ethyl acetate as a safer solvent. ... (lactide-co-glycolide) (PLGA) microspheres have been proposed for cisplatin delivery. The drug loading ...Author: Christopher S J Campbell, M Begona Delgado-Charro, Olivier Camus, Semali Perera
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