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https://journals.sagepub.com/doi/abs/10.1177/153303460500400401
Aug 01, 2005 · Cancer drug delivery is no longer simply wrapping the drug in new formulations for different routes of delivery. Knowledge and experience from other technologies such as nanotechnology, advanced polymer chemistry, and electronic engineering, are being brought together in developing novel methods of drug delivery. Advances in our knowledge of molecular biology of cancer and pathways …Author: K. K. Jain
https://journals.sagepub.com/doi/abs/10.1177/153303460500400408
Aug 01, 2005 · Nanobiotechnologies have been applied to improve drug delivery and to overcome some of the problems of drug delivery in cancer. These can be classified into many categories that include use of various nanoparticles, nanoencapsulation, targeted delivery to tumors of various organs, and combination with other methods of treatment of cancer such as radiotherapy.Author: K. K. Jain
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065247/
Recent advances in nanotechnology have offered new hope for cancer detection, prevention, and treatment. While the enhanced permeability and retention effect has served as a key rationale for using nanoparticles to treat solid tumors, it does not enable uniform delivery of these particles to all regions of tumors in sufficient quantities.Author: Rakesh K. Jain, Triantafyllos Stylianopoulos
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806395/
Drug and oxygen delivery in tumours is dependent on the organization and efficiency of perfused vessels1,2,3.Solid stress (pressure from solid tissue components) accumulates in tumours as cancer and stromal cells proliferate in a confined microenvironment created by crosslinked matrix molecules4,5,6.The matrix stores and transmits this stress throughout the tumour7, collapsing blood vessels to ...
https://www.prnewswire.com/news-releases/global-markets-for-drug-delivery-in-cancer-forecast-to-2028---includes-coverage-on-antisense-rnai-and-gene-therapy-for-cancer-301022330.html
DUBLIN, March 12, 2020 /PRNewswire/ -- The "Drug Delivery in Cancer - Technologies, Markets & Companies" report from Jain PharmaBiotech has been added to …
https://news.yahoo.com/global-markets-drug-delivery-cancer-173000014.html
Mar 12, 2020 · Drug delivery strategies vary according to the type and location of cancer. Role of drug delivery in the management of cancers of the brain, the bladder, the breast, the ovaries and the prostate are used as examples to illustrate different approaches both experimental and clinical.
https://health.usnews.com/doctors/kewal-jain-215707
Dr. Kewal K. Jain is a pediatrician in Buffalo, New York. He has been in practice for more than 20 years. Pediatricians treat children, infants, and adolescents. They are trained to meet the ...
https://clincancerres.aacrjournals.org/content/5/7/1605
Jul 01, 1999 · In a disease such as cancer, failure to treat a small fraction of cells can result in tumor regrowth. Thus, it is crucial to know which cells have been successfully treated and which have not. To determine this, high-resolution imaging of drug distribution and its physiological determinants is essential.Author: Rakesh K. Jain
https://clincancerres.aacrjournals.org/content/25/7/2024
Apr 01, 2019 · In this issue of Clinical Cancer Research, Wang and colleagues demonstrate that shear modulus, a measure of tissue stiffness measured using elastography, correlates with drug delivery in two orthotopic mouse models of pancreatic tumors ().Although increased matrix density can cause increased stiffness and hinder drug delivery, there are other aspects of the physical tumor microenvironment ...Author: Hadi T. Nia, Lance L. Munn, Rakesh K. Jain
https://www.springer.com/gp/book/9781588298911
The field of drug development and therapeutics can be overwhelmingly encyclopedic and vast. In Drug Delivery Systems, Dr. Kewal Jain and a team of experts select the most important, cutting-edge technologies used in drug delivery systems taking into account significant drugs, new technologies such as nanoparticles, and therapeutic applications.The chapters present step-by-step laboratory ...
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