Drug Delivery Gene Therapy

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Sonoporation, drug delivery, and gene therapy.

    https://www.ncbi.nlm.nih.gov/pubmed/20349823
    Ultrasound is a very effective modality for drug delivery and gene therapy because energy that is non-invasively transmitted through the skin can be focused deeply into the human body in a specific location and employed to release drugs at that site.Author: Liang Hd, Tang J, Halliwell M

Promising RNA-based cancer gene therapy using ...

    https://www.ncbi.nlm.nih.gov/pubmed/32125904
    Mar 11, 2020 · In addition, we compare the characteristics and differences of current drug delivery systems and expound the principles of selecting a drug delivery system suitable for cancer gene therapy.Expert opinion: EVs are highly biocompatible membrane structures with low cytotoxicity which provide a new choice for drug delivery in RNA-based cancer gene ...Author: Vivian Weiwen Xue, Vivian Weiwen Xue, Sze Chuen Cesar Wong, Guoqi Song, William Chi Shing Cho

Adeno-associated virus vector as a platform for gene ...

    https://www.nature.com/articles/s41573-019-0012-9
    Feb 01, 2019 · Adeno-associated virus (AAV) vectors represent the leading platform for therapeutic gene delivery, with two recombinant AAV gene therapy products having …Author: Dan Wang, Phillip W. L. Tai, Guangping Gao

Gene Therapy — A Novel Form of Drug Delivery NEJM

    https://www.nejm.org/doi/full/10.1056/NEJM199511023331808
    Gene therapy is a novel form of drug delivery that enlists the synthetic machinery of the patient's cells to produce a therapeutic agent. Using the body to treat its own disease overcomes the need ...Author: Helen M. Blau, Matthew L. Springer

Drug-delivery technology leads to sustained HIV antibody ...

    https://www.nih.gov/news-events/news-releases/drug-delivery-technology-leads-sustained-hiv-antibody-production-nih-study
    Mar 09, 2020 · The drug-delivery system developed by scientists at NIAID’s Vaccine Research Center (VRC) uses adeno-associated virus serotype 8 (AAV8) to deliver an antibody gene. AAVs — small viruses that do not cause disease in humans — have proven to …

Gene Therapy as Drug Development: Molecular Therapy

    https://www.cell.com/molecular-therapy-family/molecular-therapy/fulltext/S1525-0016(00)90040-6
    Mar 01, 2000 · It is also true that gene therapy has been held–rightly or wrongly— to be separate and special. However, the development of gene delivery shares many more similarities with drug development than it does differences. Gene therapy must be developed in the same way as for any other drug.Author: Barrie J. Carter

Drug and Gene Delivery Duke Biomedical Engineering

    https://bme.duke.edu/research/drug-gene-delivery
    Important areas in this growing field include development of delivery vehicles such as plasmids, nanoparticles, viruses, liposomes, peptide/protein complexes, and biomaterial scaffolds, as well as studies of drug and gene transport, delivery strategies, delivery barriers, and …

Gene therapy and gene delivery systems - SlideShare

    https://www.slideshare.net/SalmanHashmi10/gene-therapy-and-gene-delivery-systems
    Dec 19, 2014 · Gene therapy and gene delivery systems 1. GENES • Are carried on a chromosome • The basic unit of heredity • Encode how to make a protein • DNA …

A new gene therapy strategy, courtesy of nature ...

    https://www.sciencedaily.com/releases/2019/12/191216173700.htm
    Dec 16, 2019 · Ohio State University. (2019, December 16). A new gene therapy strategy, courtesy of nature: Scientists turn a natural cellular process into a drug-delivery system. ScienceDaily…

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