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https://www.sciencedirect.com/topics/nursing-and-health-professions/drug-delivery-system
Brain targeting drug delivery has been gained increasing attention in the past decade, ... Drug delivery to the eye is a complex process. As a self-contained system, the eye is unique in the body in many ways that affect pharmacology and toxicology. It includes several different cell types, and functions as a complete, self-contained system. ...
https://www.sciencedaily.com/releases/2015/10/151020145221.htm
Oct 20, 2015 · Researchers develop drug delivery technique to bypass blood-brain barrier: Breakthrough could help countless patients with neurological conditions that are currently hard to treat. ScienceDaily ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010371/
Jun 18, 2018 · Altogether, a challenging task in retinal drug delivery is to overcome these protective barriers of the eye and deliver the drug with minimal damage to the retinal tissues; a result, there has been a greater interest in research focused on the development of new nanotechnology-based drug delivery systems to facilitate retinal drug administration.Author: Sibo Jiang, Yesenia L Franco, Yan Zhou, Jianjun Chen
https://www.sciencedirect.com/book/9780128179093/basic-fundamentals-of-drug-delivery
Drug delivery to the brain is extremely restricted and controlled by the occurrence of the blood–brain barrier (BBB), which prevents the movement of about 98% of drugs and pharmaceuticals. This effect is caused due to the epithelial-like tight junctions (TJ) nature inside the brain endothelium.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895432/
May 01, 2010 · Ocular drug delivery has been a major challenge to pharmacologists and drug delivery scientists due to its unique anatomy and physiology. Static barriers (different layers of cornea, sclera, and retina including blood aqueous and blood–retinal barriers), dynamic barriers (choroidal and conjunctival blood flow, lymphatic clearance, and tear dilution), and efflux pumps in conjunction pose a ...Author: Ripal Gaudana, Hari Krishna Ananthula, Ashwin Parenky, Ashim K. Mitra
https://www.nibib.nih.gov/science-education/science-topics/drug-delivery-systems-getting-drugs-their-targets-controlled-manner
Drug delivery systems are engineered technologies for the targeted delivery and/or controlled release of therapeutic agents. Drugs have long been used to improve health and extend lives. The practice of drug delivery has changed dramatically in the past few decades and even greater changes are …
https://www.nature.com/articles/nrd.2015.21
Jan 22, 2016 · From blood–brain barrier to blood–brain interface: new opportunities for CNS drug delivery William A. Banks 1 Nature Reviews Drug Discovery volume 15 , pages 275 – 292 ( 2016 ) Cite this articleAuthor: William A. Banks
https://langer-lab.mit.edu/research/drug_delivery
Drug delivery . The main current theme of our lab is utilizing polymers to deliver drugs, particularly various small molecules, genetically engineered proteins, DNA and RNAi, continuously at controlled rates for prolonged periods of time. ... lung, vagina, gi tract, eye, and brain and e) synthesizing new biodegradable polymeric delivery systems ...
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