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https://www.ibiology.org/speakers-pdf/Langer392_Nat_Sup_98.pdf
Drug delivery and targeting Robert Langer When a pharmaceutical agent is encapsulated within, or attached to, a polymer or lipid, drug safety and efficacy can be greatly improved and new therapies are possible. This has provided the impetus for active study of the design of
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272876/
Aug 10, 2011 · Delivery of drug carriers to the target cells can be only a part of the whole story of successful drug targeting. Some drug carriers may have to gain access to and get inside the cytoplasm of a target cell in order to release the drug at the optimum rate for pharmacological effectiveness as in the case of gene therapy or treatment with siRNA.Author: You Han Bae, Kinam Park
https://be.mit.edu/directory/robert-langer
Robert S. Langer completed his undergraduate stidies in Chemical Engineering at Cornell University and obtained his Sc.D in Chemical Engineering at MIT. He joined MIT as Assistant Professor of Nutritional Biochemistry in 1978. Dr. Langer has written over 1,250 articles …
https://www.nature.com/articles/s41570-017-0063
Aug 09, 2017 · Polymeric nanomaterials have a rich history of applications in the selective delivery of small-molecule drugs to their biological targets. This Review discusses the evolution of drug delivery ...Author: Ashok Kakkar, Ashok Kakkar, Giovanni Traverso, Giovanni Traverso, Omid C. Farokhzad, Ralph Weisslede...
https://www.researchgate.net/publication/233911287_Drug_delivery_and_targeting
Drug delivery and targeting. ... not ideally suited for delivery over extended periods (Langer ... agents to affinity moieties and drug delivery systems capable of targeting these natural ...
https://earthsky.org/human-world/robert-langer-on-targeted-drug-delivery-for-future-of-medicine
Jul 13, 2011 · Robert Langer of M.I.T. helped pioneer targeted drug delivery systems. They are a way of getting drugs to specific parts of the body – even a specific kind of cell. Dr. Langer builds these ...Author: Beth Lebwohl
https://www.ncbi.nlm.nih.gov/pubmed/26268315
Aug 12, 2015 · Targeting drugs selectively to the inflamed intestine may improve therapeutic outcomes and minimize systemic toxicity. We report the development of an inflammation-targeting hydrogel (IT-hydrogel) that acts as a drug delivery system to the inflamed colon.Author: Sufeng Zhang, Sufeng Zhang, Joerg Ermann, Joerg Ermann, Marc D. Succi, Marc D. Succi, Marc D. Succi,...
http://www.americanpharmaceuticalreview.com/Featured-Articles/148744-Key-Targeting-Approaches-for-Pharmaceutical-Drug-Delivery/
Oct 25, 2013 · Drug targeting is defined as the ability of a drug molecule to accumulate in the target organ or tissue selectively such that the concentration of the drug at the disease site is high, while its concentration in nontarget organs and tissues is low, preferably, below certain minimal level so as to prevent any toxic effect. Thus, drug targeting can overcome the non-specific toxic effect of ...
http://www.oalib.com/references/12134356
Sep 11, 2014 · Langer R (1998) Drug delivery and targeting, in Therapeutic Horizons. ed. P. Campbell, Nature 392: 5–10. 被如下文章引用： TITLE: Solvent Free Fabrication of Micro and Nanostructured Drug Coatings by Thermal Evaporation for Controlled Release and Increased Effects
https://drugdeliveryeportfolio.wordpress.com/2014/10/30/a-critical-review-of-robert-langer-drug-delivery-and-targeting-naturevol-392-april-1998/
Oct 30, 2014 · Drug delivery and drug targeting is a scientific article written by Robert Langer for the nature publishing group. Langer uses his previously written journal articles along with external sources to compose a detailed overview of current and future lipid and polymer based drug delivery systems.
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