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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296090/
Oct 09, 2014 · A lymphatic targeted drug delivery system with a unique physiological disposition provides an effective tool for the treatment of diseases related to the lymphatic system, such as tumor metastasis, inflammation, and infectious disease. Carriers of colloid particles are viewed as the main methods to realize lymphatic targeted drug delivery.Author: Xiao-Yu Zhang, Wei-Yue Lu
https://onlinelibrary.wiley.com/doi/abs/10.1002/9781118833322.ch21
This chapter first gives a brief description of the lymphatic system, followed by a characterization of physicochemical properties of typical drug carriers and their influence on lymphatic uptake and transport, and then reviews the recent development of drug carriers for the lymphatic system delivery with a special focus on nano‐scaled ...Author: Qiuhong Yang, Laird Forrest
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732201/
Jul 26, 2013 · In the development of drug delivery to target progressive lymphatic disease, such as human malignancy, lymphatic imaging techniques play a crucial role in planning treatment. The disease invades the lymphatic system in the first stage of progression during metastasis.Author: Arshad Ali Khan, Jahanzeb Mudassir, Noratiqah Mohtar, Yusrida Darwis
https://www.nature.com/articles/s41598-019-49386-5
Sep 13, 2019 · Use of a Lymphatic Drug Delivery System and Sonoporation to Target Malignant Metastatic Breast Cancer Cells Proliferating in the Marginal Sinuses Skip …Author: Shigeki Kato, Shigeki Kato, Yuko Shirai, Maya Sakamoto, Shiro Mori, Tetsuya Kodama
https://www.sciencedirect.com/science/article/pii/S1818087613000135
That is, lymphatic drug delivery depends on the physiological processes of lipid digestion and absorption. The lipid digestion and absorption process associated with the lymphatic delivery of lipophilic drugs has been extensively reviewed [8] , [9] , [10] .Author: Hyeongmin Kim, Yeongseok Kim, Jaehwi Lee
https://www.researchgate.net/publication/319536961_Lymphatic_Delivery_Concept_Challenges_and_Applications_INDIAN_DRUGS_Best_Review_Article_Award_2017
Lymphatic Delivery: Concept, Challenges and Applications (INDIAN DRUGS Best Review Article Award 2017) The lymphatic system is an additional circulatory system throughout the entire body. It plays a critical role in the recognition of immune system and response to disease.
https://www.researchgate.net/publication/271331686_Recent_advances_in_lymphatic_targeted_drug_delivery_system_for_tumor_metastasis
The lymphatic system has an important defensive role in the human body. The metastasis of most tumors initially spreads through the surrounding lymphatic tissue and eventually forms lymphatic metastatic tumors; the tumor cells may even transfer to other organs to form other types of tumors. Clinically, lymphatic metastatic tumors develop rapidly.
https://www.monash.edu/pharm/research/areas/drug-delivery/research-areas/drug-delivery/lymphatic-absorption-and-targeted-delivery-to-the-lymphatic-system
Lymphatic absorption and targeted delivery to the lymphatic system Comprising a network of vessels, nodes and tissues throughout the vascular regions of the body, the lymphatic system plays a critical role in immune response, infection, fat metabolism, protein transport and cancer metastasis.
https://www.nature.com/articles/s41578-019-0110-7
May 02, 2019 · Materials can be used as instructive delivery vehicles to achieve accumulation of drugs in the lymph nodes and to target specific lymph node-resident cell subtypes. In this Review, we describe the compartmental architecture of lymph nodes and the cell and fluid transport mechanisms to and from lymph nodes.Author: Alex Schudel, Alex Schudel, David M. Francis, David M. Francis, Susan N. Thomas
https://www.sciencedirect.com/science/article/pii/S0169409X96004929
Conclusions The drug delivery opportunities provided by drug transport via the intestinal lymphatics include (i) increased bioavailability via a decrease in hepatic first pass metabolism, (ii) the ability to specifically target drugs to regions of the lymphatics supplied by mesenteric lymph, and (iii) a modulation in the rate of drug input to ...Author: Christopher J.H. Porter, William N. Charman
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