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https://www.sciencedirect.com/science/article/pii/S0168365902002353
Oct 30, 2002 · Double-walled microspheres for the sustained release of a highly water soluble drug: characterization and irradiation studies ... The effects of irradiation were also investigated to determine the suitability of these double-walled microspheres as delivery devices to be used in conjunction with radiotherapy. ... The double-walled polymeric drug ...Author: Teng Huar Lee, Jianjun Wang, Chi-Hwa Wang
https://www.nature.com/articles/367258a0
Jan 20, 1994 · Double-walled polymer microspheres for controlled drug release. Skip to main content. ... Challenges and Recent Progress in Oral Drug Delivery Systems for BiopharmaceuticalsAuthor: Kathleen J. Pekarek, Jules S. Jacob, Edith Mathiowitz
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622944/
Since an important goal of drug delivery systems is to attain well-controlled drug release rates, double-walled microspheres with a drug-encapsulating particle core surrounded by a drug-free shell layer are introduced [3–12].Author: Qingxing Xu, Qingxing Xu, Shi En Chin, Chi-Hwa Wang, Daniel W. Pack
https://journals.sagepub.com/doi/10.1177/2041731417735402
By encapsulating an adipogenic drug, such as dexamethasone in double-walled PLGA/PLLA microspheres, we have shown that one can achieve slow and sustained drug delivery in a local environment, resulting in a long-term effect of dexamethasone in the implanted fat tissue for over 6 …Author: Arta Kelmendi-Doko, J Peter Rubin, Katarina Klett, Christopher Mahoney, Sheri Wang, Kacey G Marra
https://www.semanticscholar.org/paper/FORMULATION-AND-EVALUATION-OF-DOUBLE-WALLED-LOADED-Babu-Teja/ba81d8950e071805f8f7b1935e0f548b1d7e851b
Pantoprazole is an acid labile drug, which can be degraded in the stomach. Therefore, the drug should be targeted to intestine; to bypass the stomach the gastro resistant double walled microspheric drug delivery system was adopted. The formulations were developed consisting of double wall.
https://www.sciencedirect.com/science/article/pii/S0168365904000252
The goal of this work was to fabricate uniform double-walled microspheres comprising PCPH cores and PLG shells designated PLG(PCPH), as well as PLG cores and PCPH shells designated PCPH(PLG), each exhibiting a controllable shell thickness, as a means to …Author: Cory Berkland, Emily Pollauf, Daniel W Pack, Kyekyoon (Kevin) Kim
https://link.springer.com/chapter/10.1007%2F978-0-387-25842-3_2
Thus, there is a corresponding need for safer and more effective methods and devices for drug delivery. Indeed, drug delivery systems—designed to provide a therapeutic agent in the needed amount, at the right time, to the proper location in the body, in a manner that optimizes efficacy, increases compliance and minimizes side effects—were ...Author: Kyekyoon Kevin Kim, Daniel W. Pack
https://www.mdpi.com/2073-4360/9/10/485/pdf
In double-walled microspheres, drug encapsulated in the interior cover is surrounded by a drug-free outer layer that overcomes most of the problems stated above [13–15]. In this case, the drug-free outer layer acts as an additional diffusion barrier inhibiting the drug from leaking out during the microspheres fabrication process.Author: Rezaul H. Ansary, Rezaul H. Ansary, Mohd. Mokhlesur Rahman, Mohd. Mokhlesur Rahman, Nasir A.N. Moham...
https://pdfs.semanticscholar.org/76cc/2635ad9c2fe576e3736f8e2716060b750a90.pdf
resistant drug delivery system for pantoprazole. Pantoprazole is an acid labile drug, which can be degraded in the stomach. Therefore, the drug should be targeted to intestine; to bypass the stomach the gastro resistant double walled microspheric drug delivery system was adopted. The formulations were developed consisting of double wall.
https://www.slideshare.net/gajendragupta75491/microspheres-as-drug-delivery-system
Mar 13, 2013 · Microspheres as drug delivery system 28,378 views. Share; Like; Download ... LM provides a control over coating parameters in case of double walled microspheres. The microspheres structures can be visualized before and after coating and the change can be measured microscopically. SEM allows investigations of the microspheres surfaces and after ...
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