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https://www.sciencedirect.com/topics/medicine-and-dentistry/acidosis
Oxygen delivery to tissues. Acidosis causes a right shift in the oxyhaemoglobin dissociation curve (the Bohr effect, see p. 90) and this facilitates oxygen delivery to tissues. An increase in hydrogen ion concentration decreases erythrocyte 2,3-diphosphoglycerate (2,3-DPG) concentrations through effects on both synthesis and breakdown; this ...
https://healthjade.net/alkalosis/
Acidosis vs alkalosis. Normal blood pH must be maintained within a narrow range, typically 7.35-7.45 (average 7.40), to ensure the proper functioning of metabolic processes and the delivery of the right amount of oxygen to tissues.
https://www.healthline.com/health/alkalosis
Alkalosis occurs when your body has too many bases. It can occur due to decreased blood levels of carbon dioxide, which is an acid. ... Your treatment plan will depend on the cause of your alkalosis.
http://anaesthesiamcq.com/AcidBaseBook/ab7_4.php
The body’s major compensatory response to impaired tissue oxygen delivery is to increase cardiac output but this ability is impaired if hypovolaemia and decreased myocardial contractility are present. Give oxygen! The need for administration of supplemental oxygen to patients with metabolic alkalosis is a neglected part of therapy.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207677/
Jan 03, 2017 · The most dreaded consequence of hypokalemia is arrhythmias, including ventricular fibrillation. Another (often) less-considered effect of alkalosis is a decreased oxygen delivery to tissues as the oxyhemoglobin dissociation curve is shifted to the left. Alkalosis is also a potent vasoconstrictor, leading to further tissue hypoxia .Author: Simon Kreü, Simon Kreü, Allan Jazrawi, Jan Miller, Amir Baigi, Michelle Chew
https://www.sciencedirect.com/topics/veterinary-science-and-veterinary-medicine/respiratory-alkalosis
Respiratory alkalosis or primary hypocapnia is characterized by decreased P co 2, increased pH, and a compensatory decrease in HCO 3 − concentration in the blood. Respiratory alkalosis occurs whenever the magnitude of alveolar ventilation exceeds that required to eliminate the CO 2 produced by metabolic processes in the tissues.
https://www.ncbi.nlm.nih.gov/books/NBK526028/
This process usually takes place in peripheral tissues, as the desired effect is to unload oxygen into these tissues and load oxygen in the lungs. To limit the decrease in pH of the environment surrounding peripheral tissues, hemoglobin serves as a buffering agent by releasing its oxygen molecules in …Author: Aakash K. Patel, Andrew Benner, Jeffrey S. Cooper
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