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https://www.sciencedirect.com/science/article/pii/S0142961207010605
Dissolving microneedles for transdermal drug delivery. (a) Microneedle master-structure (600 μm in height and 300 μm wide at base) used to mold dissolving microneedles made of (b) CMC, (c) amylopectin and (d) BSA. The master-structure was imaged by scanning electron microscopy and the molded microneedles were imaged by brightfield microscopy.Author: Jeong Woo Lee, Jung-Hwan Park, Mark R. Prausnitz
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2293299/
Dissolving microneedles for transdermal drug delivery. ... using pyramidal microneedles with a small aspect ratio can provide added mechanical strength for mechanically weak biomaterials like CMC. However, microneedles with an aspect ratio that is too small will also have poor insertion due to fabrication difficulties to make a sharp tip and ...Author: Jeong Woo Lee, Jung-Hwan Park, Mark R. Prausnitz
https://www.ncbi.nlm.nih.gov/pubmed/18261792
1. Biomaterials. 2008 May;29(13):2113-24. doi: 10.1016/j.biomaterials.2007.12.048. Epub 2008 Feb 7. Dissolving microneedles for transdermal drug delivery.Author: Jeong Woo Lee, Jung-Hwan Park, Mark R. Prausnitz
https://www.sciencedirect.com/science/article/pii/S0753332217324149
Although microneedles have been investigated for transdermal drug delivery since 1998 , the device has not yet been approved by regulatory authorities for use in the clinic. One of the main challenges regarding the use of dissolving microneedles in humans is that only a …Author: Kevin B. Ita
https://www.nature.com/articles/s41598-019-44418-6
May 27, 2019 · The interest in safe and efficient transdermal drug delivery systems has been increasing in recent decades. In light of that, polymeric dissolving …Author: Shayan Fakhraei Lahiji, Youseong Kim, Geonwoo Kang, Suyong Kim, Seunghee Lee, Hyungil Jung
https://www.ondrugdelivery.com/dissolvable-microneedles-applications-opportunities/
Ito Y et al, “Self-dissolving microneedles for the percutaneous absorption of EPO in mice”. J Drug Target, 2006, Vol 14(5), pp 255-261. Lee JW, Park JH, Prausnitz MR, “Dissolving microneedles for transdermal drug delivery”. Biomaterials, 2008, Vol 29(13), pp 2113-2124. Prausnitz MR, Langer R, …
https://www.researchgate.net/publication/5590016_Lee_JW_Park_JH_and_Prausnitz_MR_Dissolving_microneedles_for_transdermal_drug_delivery_Biomaterials_29_2113-2124
Dissolving microneedles for transdermal drug delivery. Biomaterials 29: 2113-2124 Article (PDF Available) in Biomaterials 29(13):2113-24 · June 2008 with 148 Reads
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