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http://www.pharmtech.com/how-can-we-improve-dissolution-testing-transdermals
Sep 15, 2010 · Transdermal systems also could benefit pharmaceutical companies that seek to reformulate their drugs for delivery by alternate routes, thus extending the lives of their patents. Dissolution testing can help manufacturers confirm that a dosage form releases the correct amount of drug at the intended rate.
https://www.ncbi.nlm.nih.gov/pubmed/18997767
Transdermal drug delivery has made an important contribution to medical practice, but has yet to fully achieve its potential as an alternative to oral delivery and hypodermic injections. First-generation transdermal delivery systems have continued their steady increase in clinical use for delivery of small, lipophilic, low-dose drugs.Author: Mark R Prausnitz, Robert Langer
http://dissolutiontech.com/DTresour/201011Articles/DT201011_A02.pdf
the test methods that should be employed to ensure the quality and performance of topical and transdermal drug products. The term topical drug products refers to all formulations applied to the skin except transdermal delivery systems (TDS) or transdermal patches that will be addressed separately. Topical dosage forms include solutions (for which
https://biomeddermatol.biomedcentral.com/articles/10.1186/s41702-020-0058-7
Transdermal delivery systems have been intensively studied over the past 2 decades, with the focus on overcoming the skin barrier for more effective application of pharmaceutical and cosmetic products. Although the cosmeceutical industry has made a substantial progress in the development and incorporation of new and effective actives in their products, the barrier function of the skin remains ...
http://dissolutiontech.com/DTresour/1995Articles/DT199502_A03.pdf
Dissolution Performance Testing Of Transdermal Systems skin or whether there is any perme ation through skin. If there is perme ation. the rates can be determined and evaluated. An example of the value of such experiments was the determina tion of preferred skin site for place ment of the scopolamine transdermal system.
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