Development And Scale-Up Of A Microsphere Protein Delivery System

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Development and Scale-up of a Microsphere Protein Delivery ...

    http://onlinelibrary.wiley.com/doi/10.1021/bp9701271/abstract
    This paper reviews the development path for the ProLease injectable microsphere delivery system for proteins using human growth hormone as an example. The …

Development and Scale‐up of a Microsphere Protein Delivery ...

    https://aiche.onlinelibrary.wiley.com/doi/pdf/10.1021/bp9701271
    Development and Scale‐up of a Microsphere Protein Delivery System. Mark A. Tracy. Alkermes, Inc., 64 Sidney Street, Cambridge, Massachusetts 02139 ... This paper reviews the development path for the ProLease injectable microsphere delivery system for proteins using human growth hormone as an example. The process consists of four stages, the ...Author: Mark A. Tracy

Development of protein delivery microsphere system by a ...

    https://www.researchgate.net/publication/23296602_Development_of_protein_delivery_microsphere_system_by_a_novel_SOOW_multi-emulsion
    The preparation of a 5-FU microsphere delivery system by a solid-in-oil-in-hydrophilic oil (S/O/hO) novel method was carried out and then in vitro and in vivo evaluation of the 5-FU-microsphere ...

Developments in human growth hormone preparations ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122423/
    Jul 25, 2014 · Developments in human growth hormone preparations: sustained-release, prolonged half-life, novel injection devices, and alternative delivery routes ... Leitner et al developed a nasal microparticulate delivery system with thiomer polycarbophil-cysteine, ... Development and scale-up of a microsphere protein delivery system. Biotechnol Prog. 1998 ...Author: Yunpeng Cai, Mingxin Xu, Minglu Yuan, Zhenguo Liu, Weien Yuan

Freeze-drying of microparticulates in a vibro-separator

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2750470/
    These references are in PubMed. This may not be the complete list of references from this article. ... Jeyanthi R, Calis S, Thanoo BC, Burton KW, DeLuca PP. Biodegradable microspheres as depot system for parenteral delivery of peptide drugs. J Contr Rel. 1994; 29:375–384 ... Development and scale-up of a microsphere protein delivery system ...Author: Kyu-Heum Na, Byung Ho Woo, Yeong Woo Jo, Azar M. Hazrati, Patrick P. DeLuca

(PDF) Microspheres as delivery systems for the controlled ...

    https://www.researchgate.net/publication/237489123_Microspheres_as_delivery_systems_for_the_controlled_release_of_peptides_and_proteins
    Microspheres as delivery systems for the controlled release of peptides and proteins. ... Tracy M. Development and scale-up. of a microsphere protein delivery system.

Microspheres for Drug Delivery SpringerLink

    https://link.springer.com/chapter/10.1007%2F978-0-387-25842-3_2
    Development and scale-up of a microsphere protein delivery system. Biotechnol. Prog ... Investigation on preparation and protein release of biodegradable polymer microspheres as drug-delivery system. J. App. Polymer Sci., 84(4):778–784 ... Microspheres for Drug Delivery. In: Ferrari M., Lee A.P., Lee L.J. (eds) BioMEMS and Biomedical ...Author: Kyekyoon Kevin Kim, Daniel W. Pack

Poly(ethylene glycol)-Modified Proteins: Implications for ...

    https://link.springer.com/article/10.1208%2Fs12248-009-9081-8
    Feb 06, 2009 · Further, protein activity may be lost due to the damaging effects of protein-interface and protein-surface interactions that occur during both microsphere formation and release. Several techniques are discussed in this review that may improve the …Author: Sheetal S. Pai, Robert D. Tilton, Todd M. Przybycien

PowerPoint Presentation

    http://drugdeliveryexperts.com/wp-content/uploads/2015/03/DDE-Introduction-20180727-1.pdf
    Delivery System . Selection. Drug Product Development. Molecule Design. Peptide/Protein Variants. Conjugates for Half-Life. Delivery System Design. Aqueous or Non-Aqueous Vehicle. Sustained Release Formulation. Triggered or Targeted Systems. Drug Product Design. Pen/Auto-Injector. Pre-Filled Syringe. Nasal/Ocular Drops/Spray. Lead Molecule ...

[Full text] Developments in human growth hormone ...

    https://www.dovepress.com/developments-in-human-growth-hormone-preparations-sustained-release-pr-peer-reviewed-fulltext-article-IJN
    Developments in human growth hormone preparations: sustained-release, prolonged half-life, novel injection devices, and alternative delivery routes Yunpeng Cai,1,2 Mingxin Xu,2 Minglu Yuan,2 Zhenguo Liu,1 Weien Yuan2 1Department of Neurology, Xinhua Hospital, School of Medicine, 2School of Pharmacy, Shanghai Jiao Tong University, Shanghai, People’s Republic of China Abstract: Since the ...

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