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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666240/
A significant plan is executed in the present study to study the effect of double-compression coating on flurbiprofen core mini-tablets to achieve the pulsatile colonic delivery to deliver the drug at a specific time as per the patho-physiological need of the disease that results in improved therapeutic efficacy.Author: Sateesh Kumar Vemula
https://www.ncbi.nlm.nih.gov/pubmed/22845842
Formulation, evaluation and pharmacokinetics of colon targeted pulsatile system of flurbiprofen. Veerareddy PR(1), Vemula SK. Author information: (1)Department of Pharmaceutics, Chaitanya College of Pharmacy Education and Research , Kishanpura, Hanamkonda, Warangal, Andhra Pradesh, India. [email protected]: Prabhakar Reddy Veerareddy, Sateesh Kumar Vemula
https://www.researchgate.net/publication/230587683_Formulation_evaluation_and_pharmacokinetics_of_colon_targeted_pulsatile_system_of_flurbiprofen
Formulation, evaluation and pharmacokinetics of colon targeted pulsatile system of flurbiprofen Article in Journal of Drug Targeting 20(8):703-14 · September 2012 with 311 Reads How we measure ...
https://www.researchgate.net/publication/247774253_Pulsatile_Drug_Delivery_System_Drugs_used_in_the_Pulsatile_Formulations
A blend of floating and pulsatile principles of drug delivery system would have the advantage that a drug can be released in the upper GI tract after a definite time period of no drug release.
https://www.semanticscholar.org/paper/Formulation-and-evaluation-of-press-coated-sodium-PatilSVPatilSSSahooS-JanugadeB./c9af3f91b136bbd42fc91aa2f77bfe73dd9be0f9/figure/0
Table 1: Formulations of core tablet. - "Formulation and evaluation of press-coated montelukast sodium tablets for pulsatile drug delivery system"
https://sciforschenonline.org/journals/pharmaceutical-analytics-insights/article-data/JPAI-1-104/JPAI-1-104.pdf
tromethamine [4], colon targeted pulsatile system of flurbiprofen for colonic inflammation [5], pulsatile systems for targeted drug delivery of celecoxib for prophylaxis of colorectal cancer [6], time and pH dependent colon specific, pulsatile delivery of theophylline for nocturnal asthma [7].
https://www.semanticscholar.org/paper/Formulation-and-evaluation-of-press-coated-sodium-PatilSVPatilSSSahooS-JanugadeB./c9af3f91b136bbd42fc91aa2f77bfe73dd9be0f9
An oral press-coated tablet was prepared by using direct compression and wet granulation methods to achieve the predetermined lag time. This press-coated tablet containing montelukast sodium in the inner core was formulated with an outer barrier layer by different compositions of hydrophobic polymer ethylcellulose and hydrophilic polymer low-substituted hydroxypropylcellulose. The effect of ...
https://sciforschenonline.org/journals/pharmaceutical-analytics-insights/JPAI-1-104.php
Flurbiprofen Pulsatile Colon-Specific Delivery: Formulation and Evaluation of DoubleCompression Coated Tablets. Sateesh Kumar Vemula 1,2* Vijaya Kumar Bontha 3 . 1 Department of Pharmacy, College of Medical and Health Sciences, Wollega University, Post Box No: 395, Nekemte, Ethiopia
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