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https://www.researchgate.net/publication/301981987_Design_and_Development_of_Systemic_Oral_Mucosal_Drug_Delivery_Systems
Chitosan, as a mucoadhesive biopolymer has become a very promising material in development of oral mucosal delivery systems, which can be prepared in various forms such as gels, films, sponges ...
https://link.springer.com/chapter/10.1007%2F978-1-4899-7558-4_7
Mar 14, 2015 · Rathbone M., Şenel S., Pather I. (2015) Design and Development of Systemic Oral Mucosal Drug Delivery Systems. In: Rathbone M., Senel S., Pather I. (eds) Oral Mucosal Drug Delivery and Therapy. Advances in Delivery Science and Technology.Author: Michael John Rathbone, Sevda Şenel, Indiran Pather
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255397/
In recent years, many such mucoadhesive drug delivery systems have been developed for oral, buccal, nasal, rectal and vaginal routes for both systemic and local effects. Dosage forms designed for mucoadhesive drug delivery should be small and flexible enough to be acceptable for patients and should not cause irritation.
http://ijpsr.com/bft-article/a-detailed-review-on-oral-mucosal-drug-delivery-system/?view=fulltext
Structure and Design of Oral mucosal Dosage Form 16, 17, 18: Matrix type: The buccal patch designed in a matrix configuration contains drug, adhesive,... Reservoir type: The buccal patch designed in a reservoir system contains a cavity for...
https://journal.pda.org/content/66/5/466
Sep 01, 2012 · Mucoadhesive drug delivery gives facility to include a permeation enhancer/enzyme inhibitor or pHmodifier in the formulation and versatility in designing as multidirectional or unidirectional release systems for local and systemic action.Author: Dattatraya Manohar Shinkar, Avinash Sridhar Dhake, Chitral Mallikarjuna Setty
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/oral-drug-delivery
Oral drug delivery (ODD) is the most preferred and convenient route of drug administration due to high patient compliance, cost-effectiveness, least sterility constraints, flexibility in the design of dosage form and ease of production. However, the challenges faced in oral drug delivery include poor bioavailability of drug, which is determined by three vital factors, namely, dissolution, permeability, and solubility.
http://www.authorstream.com/Presentation/salunkeamarjit-847699-amar-presentation-mdds/
Feb 21, 2011 · By this definition, the mucosal routes for drug delivery are: Buccal / Oral route Nasal route Ocular route Vaginal route Gastrointestinal route Monday, February 21, 2011 3 Slide 4: ADHESION : It can be defined as bond produced by contact between a pressure sensitive adhesive and surface MUCOADEHSION: When adhesive attachment is to a mucous coat, then the phenomenon is …
https://www.medscape.com/viewarticle/817508_2
Oct 23, 2019 · Impact of Mucosal Delivery. The design of the new nanoscale-based drug delivery systems, and the combination of the different types of auxiliary agents and strategies that lower the mucus barrier ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436075/
The strategies studied to overcome such obstacles include the employment of new materials that, possibly, combine mucoadhesive, enzyme inhibitory and penetration enhancer properties and the design of innovative drug delivery systems which, besides improving patient compliance, favor a more intimate contact of the drug with the absorption mucosa.Author: P Chinna Reddy, Chaitanya K.S.C., Y Madhusudan Rao
https://www.slideshare.net/shivadheeraj/buccal-drug-delivery-system-14721771
Oct 14, 2012 · DRUG DELIVERY PATHWAYSTwo possible routes of drug absorption through oral mucosa 9. BUCCAL DRUG DELIVERY AND MUCOADHESIVITYMucoadhesion of the device is a key elementThe term ‘mucoadhesive’ is commonly used for materials that bind to the mucin layer of a biological membraneAchieve systemic delivery of drugs include tablets, patches, tapes, films, …
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