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https://www.sciencedirect.com/science/article/pii/S0378517315304622
In practice, it not straightforward for a formulator to be aware of the various technical advances made in this field, which is gaining more and more interest. Thus, a particular aim of this review is to give an overview on the pragmatic tools, which can be used for designing customized drug delivery systems using 3D printing.Author: Jonathan Goole, Karim Amighi
https://www.nibib.nih.gov/science-education/science-topics/drug-delivery-systems-getting-drugs-their-targets-controlled-manner
Drug delivery systems are engineered technologies for the targeted delivery and/or controlled release of therapeutic agents. Drugs have long been used to improve health and extend lives. The practice of drug delivery has changed dramatically in the past few decades and even greater changes are …
https://www.aiche.org/resources/publications/cep/2018/may/designing-drug-delivery-systems-articular-joints
Designing Drug Delivery Systems for Articular Joints. No disease-modifying drug exists for osteoarthritis due to poor drug delivery within joints. Engineered biomaterials could address this challenge by improving the duration and targeting of therapies.
https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-018-0392-8
Sep 19, 2018 · Interestingly, each of these drug delivery systems has its own chemical, physical and morphological characteristics, and may have affinity for different drugs polarities through chemical interactions (e.g., covalent bonds and hydrogen bonds) or physical interactions (e.g., electrostatic and van der Waals interactions).Author: Jayanta Kumar Patra, Gitishree Das, Leonardo Fernandes Fraceto, Leonardo Fernandes Fraceto, Estefani...
https://www.mddionline.com/designing-drug-delivery-device-read-first
Jul 22, 2019 · While designing the drug delivery device, there are two sub-systems needs to be taken into consideration. One is the primary container system, which directly comes in contact with the drug formulation. The other is the injection, delivery, and needle retraction mechanism. The latter part can be made either manual or automatic.
https://www.sciencedirect.com/science/article/pii/B9780128179093000017
1.1. Conventional Drug Delivery Systems and Limitations. In addition to the acceptable patient compliance, the purpose of drug delivery systems is to maximize the therapeutic efficacy of the incorporated drug(s) by the means of bioavailability enhancement or minimization of adverse effects.Author: Anu Hardenia, Neha Maheshwari, Shiv Shankar Hardenia, Sunil Kumar Dwivedi, Rahul Maheshwari, Rakesh ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142099/
Sep 28, 2014 · The controlled drug delivery technology has progressed over the last six decades. It began in 1952 with the introduction of the first sustained release formulation. The 1st generation (1950-1980) of drug delivery was focused on developing oral and transdermal sustained release systems and establishing the controlled drug release mechanisms.Author: Kinam Park
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425796/
Aug 12, 2012 · Among alternative experimental delivery systems of paclitaxel, nanoparticles of various biodegradable polymers and bioadhesive materials have been considered as promising. Nanotechnology can help to improve the bioavailability of poorly soluble drugs such as paclitaxel, enhancing drug delivery . Nanoparticles also have the ability to permeate ...Author: Madhu S. Surapaneni, Sudip K. Das, Nandita G. Das
https://www.medindia.net/patients/patientinfo/drug-delivery-system.htm
Drug delivery systems, is a technology using various chemicals to bind the target drugs, carry them to target organ, tissue or cell where the drug is released at a pre-determined rate.
https://www.medicaldesignbriefs.com/component/content/article/mdb/features/technology-leaders/23089
Oct 01, 2015 · A drug delivery pump can be engineered to allow infusion to continue without interruption or failure, minimizing risk, inconvenience and discomfort for the patient. One example is a pump that has a flow-activated safety valve that shuts off drug flow to the patient in the event a high flow rate occurs during an MRI procedure.
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